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Merck
CN

93422

Triton™ X-114

别名:

(1,1,3,3-四甲基丁基)苯基-聚乙二醇, 聚乙二醇叔辛基苯基醚

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关于此项目

线性分子式:
(C2H4O)n C14H22O, n = 7 or 8
化学文摘社编号:
9036-19-5
UNSPSC Code:
12161900
NACRES:
NA.21
PubChem Substance ID:
57653556
MDL number:
MFCD00128254
Beilstein/REAXYS Number:
2315025

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InChI key

HNLXNOZHXNSSPN-UHFFFAOYSA-N

SMILES string

CC(C)(C)CC(C)(C)c1ccc(OCCOCCOCCOCCOCCOCCOCCO)cc1

InChI

1S/C28H50O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h6-9,29H,10-24H2,1-5H3

description

non-ionic

form

liquid

mol wt

average mol wt 537

impurities

≤0.001% peroxides (as H2O2)
≤1% water

ign. residue

≤0.2%

refractive index

n20/D 1.488 (lit.)
n20/D 1.495

CMC

0.2 mM (20-25°C)

transition temp

pour point ~−9 °C
cloud point 23 °C

anion traces

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤15 mg/kg
K: ≤500 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤500 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

HLB

12.4

Quality Level

200

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相关类别

Application

Triton™ X-114用于：
  • 整合膜蛋白的相分离
  • 细菌包涵体的纯化
  • 研究两亲性吩噻嗪类药物盐酸异丙嗪的混浊现象
  • 蛋白印迹前将条件培养基分成不溶性和可溶性相
  • 溶解来自牛脑的磷脂酰肌醇4-磷酸5-激酶

General description

Triton™ X-114是一种非离子型洗涤剂。它是可溶解具有可逆相分离性质的膜的良好洗涤剂，可用于分离内在膜蛋白。Triton™ X-114溶液在0℃是均相的，但在20℃以上发生相分离，形成水相和洗涤剂相。Triton™ X-114溶液中蛋白的相分离已经过研究。该辛基酚乙氧基化物与阴离子、阳离子和其他非离子型表面活性剂相容，在大多数酸性和碱性溶液中化学稳定。

Legal Information

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

483.8 °F - closed cup

flash_point_c

251 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCZ8321
MKCV9212
MKCT8848
MKCS2583
MKCP2867

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Cloud point variation of amphiphilic drug promethazine hydrochloride with added surfactants.
Naqvi A Z and Khatoon S
Colloids and Surfaces. B, Biointerfaces, 88(2), 568-573 (2011)
Extraction and identification of human platelet integral membrane proteins using Triton X-114.
P J Newman et al.
Thrombosis research, 27(2), 221-224 (1982-07-15)
Expression, purification and immunological characterization of the transforming protein E7, from cervical cancer-associated human papillomavirus type 16.
Fernando G J P, et al.
Clinical and Experimental Immunology, 115(3), 397-397 (1999)
M Schmidt et al.
FEBS letters, 325(3), 201-204 (1993-07-05)
Phosphatidylinositol 4-phosphate 5-kinase is associated with bovine brain microsomes to an extent of approximately 65% of the total cellular enzyme activity. This membrane-associated kinase activity can be solubilized with Triton X-114. Following polyacrylamide gel electrophoresis in the presence of SDS
A Sánchez-Ferrer et al.
Plant physiology, 91(4), 1481-1487 (1989-12-01)
Polyphenoloxidase from grape berries is extracted only by nonionic detergents with a hydrophilic-lipophilic balance between 12.4 and 13.5. The enzyme was partially purified in latent form, free of phenolics and chlorophylls, by using temperature phase partitioning in a solution of
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