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Merck
CN

94258

Sigma-Aldrich

圣草酚

≥95.0% (HPLC)

别名:

3′,4′,5,7-四羟基黄酮

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关于此项目

经验公式(希尔记法):
C15H12O6
化学文摘社编号:
分子量:
288.25
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.25
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质量水平

方案

≥95.0% (HPLC)

表单

powder

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

−20°C

SMILES字符串

O=C1C2=C(O)C=C(O)C=C2OC(C3=CC=C(O)C(O)=C3)C1

InChI

1S/C15H12O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-5,13,16-19H,6H2

InChI key

SBHXYTNGIZCORC-UHFFFAOYSA-N

一般描述

圣草酚是一种能掩盖苦味的膳食类黄酮,主要由北美圣草(Eriodictyon californicum)和毛建草(Dracocephalum rupestre)提取,但也存在于许多柑橘类水果、药用植物和蔬菜中。

应用

圣草酚还可用于从肥大细胞脱颗粒和神经酰胺激酶活性方面研究其抑制IgE/Ag诱导I型超敏反应的机制。它也可用于通过激活Nrf2/ARE信号通路研究其潜在的抗糖尿病和神经保护活性。

生化/生理作用

圣草酚在体内吸收缓慢,在血浆和尿液中以共轭形式的高圣草酚存在。它具有抗氧化、抗炎、抗癌、抗糖尿病、抗肥胖、神经保护、心脏保护和肝脏保护等多种药理作用。

包装

无底玻璃瓶。内含物装在插入的融合锥内。

其他说明

此产品我们采用非立体特异性的CAS号。虽然该物质主要由天然对映体构成,但它在溶液中很容易发生消旋作用。因此该产品并不能保证一定是立体特异性的,建议只将其用于非立体特异性分析。

储存分类代码

11 - Combustible Solids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ángel Amesty et al.
Journal of natural products, 74(5), 1061-1065 (2011-04-21)
Three new benzodihydrofurans (1-3) and seven known aromatic compounds (4-10) were isolated from the roots of Cyperus teneriffae. Vibrational circular dichroism spectroscopy was used to define the absolute configuration of 1.
Minpei Kuroda et al.
Natural product communications, 7(4), 471-474 (2012-05-12)
MeOH extracts of 37 herbs were tested in screening experiments for rat intestinal alpha-glucosidase. The MeOH extract of the aerial parts of Scutellaria lateriflora L. (Lamiaceae) significantly inhibited sucrase and maltase activities, using sucrose and maltase as the substrates. Enzyme
Anowarul Islam et al.
Archives of pharmacal research, 43(6), 582-592 (2020-07-01)
Eriodictyol is a flavonoid in the flavanones subclass. It is abundantly present in a wide range of medicinal plants, citrus fruits, and vegetables that are considered to have potential health importance. Having the considerable medicinal properties, eriodictyol has been predicted
Zirong Deng et al.
Evidence-based complementary and alternative medicine : eCAM, 2020, 6681352-6681352 (2021-01-09)
Eriodictyol is a flavonoid that belongs to a subclass of flavanones and is widespread in citrus fruits, vegetables, and medicinally important plants. Eriodictyol has been anticipated to explain the method of its activity via multiple cellular signaling cascades. Eriodictyol is
Emerson de Oliveira Ferreira et al.
Behavioural brain research, 312, 321-332 (2016-06-30)
Cerebral ischemia is a common disease and one of the most common causes of death and disability worldwide. The lack of glucose and oxygen in neuronal tissue leads to a series of inflammatory events, culminating in neuronal death. Eriodictyol is

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