94330
尿苷-5′-二磷酸 二钠盐 水合物
≥96.0% (HPLC), synthetic, powder
别名:
5′-UDP-Na2
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关于此项目
经验公式（希尔记法）:
C9H12N2Na2O12P2 · xH2O
化学文摘社编号:
分子量:
448.12 (anhydrous basis)
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
248-678-9
MDL number:
Beilstein/REAXYS Number:
8817400
Assay:
≥96.0% (HPLC)
Biological source:
synthetic
Form:
powder
Storage temp.:
−20°C
产品名称
尿苷-5′-二磷酸 二钠盐 水合物, ≥96.0% (HPLC)
InChI key
RHBXRWOXLRCWIZ-LLWADOMFSA-L
InChI
1S/C9H14N2O12P2.2Na.H2O/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18);;;1H2/q;2*+1;/p-2/t4-,6-,7-,8-;;;/m1.../s1
SMILES string
[Na+].[Na+].[H]O[H].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
biological source
synthetic
assay
≥96.0% (HPLC)
form
powder
impurities
≤15% water
storage temp.
−20°C
Quality Level
Application
尿苷5′-二磷酸二钠盐水合物用于：
- 作为通过液相质谱联用(LC/MS)测定小鼠肿瘤间质液间质液中代谢物水平的标准品
- 作为通过液相色谱-高分辨质谱测定法(LC-HRMS)分析核苷酸的UDP标准品
- 体外处理E6.5视网膜外植体，以研究其对小胶质细胞进入和延伸至胚胎鹌鹑视网膜的影响
Biochem/physiol Actions
尿苷5′-二磷酸(UDP)是一种由受损细胞生成的内源性信号分子，以吸引巨噬细胞。UDP促进小胶质细胞的趋化作用和化学增活，以应对神经元损伤。UDP可用作P2Y受体的配体。UDP和尿苷5′-三磷酸(UTP)可用于研究核酸(RNA)生物合成和细胞信号转导。UDP是一种核苷酸，通过磷酸化使UTP成为酶的底物，如RNA聚合酶和GTP酶。这些酶应用范围广泛，从RNA的合成到G蛋白偶联受体(GPCR)和诸如通过鸟嘌呤核苷酸交换因子(GEF)的Rho信号传递等细胞信号分子的调节等。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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