94956
二氧化乙烯基环己烯
purum, suitable for electron microscopy, mixture of isomers, ≥96.0% (GC)
别名:
4-乙烯基-1-环己烯二环氧化物, 3-环氧乙基-7-氧杂二环[4,1,0]庚烷
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关于此项目
经验公式（希尔记法）:
C8H12O2
化学文摘社编号:
分子量:
140.18
UNSPSC Code:
12162002
NACRES:
NA.25
PubChem Substance ID:
EC Number:
203-437-7
Beilstein/REAXYS Number:
106071
MDL number:
产品名称
二氧化乙烯基环己烯, purum, suitable for electron microscopy, mixture of isomers, ≥96.0% (GC)
InChI key
OECTYKWYRCHAKR-UHFFFAOYSA-N
InChI
1S/C8H12O2/c1-2-6-7(10-6)3-5(1)8-4-9-8/h5-8H,1-4H2
SMILES string
C1CC2OC2CC1C3CO3
grade
purum
assay
≥96.0% (GC)
form
liquid
technique(s)
electron microscopy: suitable
refractive index
n20/D 1.477 (lit.)
n20/D 1.479
bp
230-232 °C (lit.)
density
1.094 g/mL at 25 °C (lit.)
Quality Level
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Application
乙烯基环己烯二氧化物（VCD）可用于研究和了解其对卵巢卵泡的影响和对上皮分化的影响。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Muta. 2 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
224.6 °F - closed cup
flash_point_c
107 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Lida P Hariri et al.
Cancer biology & therapy, 10(5), 438-447 (2010-11-26)
Determining if an ovarian mass is benign or malignant is an ongoing clinical challenge. The development of reliable animal models provides means to evaluate new diagnostic tools to more accurately determine if an ovary has benign or malignant features. Although
Tracey A Van Kempen et al.
Brain research, 1379, 176-187 (2011-01-08)
Current rodent models of menopause fail to adequately recapitulate the menopause transition. The intact aging model fails to achieve very low estrogen levels, and the ovariectomy model lacks a perimenopause phase. A new rodent model of accelerated ovarian failure (AOF)
Aileen F Keating et al.
Biology of reproduction, 84(4), 743-751 (2010-11-16)
4-Vinylcyclohexene diepoxide (VCD), an occupational chemical that specifically destroys primordial and small primary follicles in the ovaries of rats and mice, is thought to target an oocyte-expressed tyrosine kinase receptor, Kit. This study compared the temporal effect of VCD on
Melissa J Romero-Aleshire et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 297(3), R587-R592 (2009-05-15)
Factors comprising the metabolic syndrome occur with increased incidence in postmenopausal women. To investigate the effects of ovarian failure on the progression of the metabolic syndrome, female B(6)C(3)F(1) mice were treated with 4-vinylcyclohexene diepoxide (VCD) and fed a high-fat (HF)
Sarah M Greising et al.
Experimental gerontology, 46(8), 685-693 (2011-05-17)
Estradiol (E(2)) treatment in young adult, ovariectomized mice increases physical activity and reverses deleterious effects on skeletal muscle. Here we test the hypothesis that E(2) treatment improves muscle function and physical activity in aged, ovarian-senescent mice. Plasma E(2) levels and
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