95098
(E)-1-羟基-2-甲基-2-丁烯基4-焦磷酸酯 锂盐
≥95.0% (TLC)
别名:
(E)-4-羟基-3-甲基-2-烯基二磷酸酯 锂盐, 1-羟基-2-甲基-2-(E)-丁烯基-4-二磷酸酯, HDMAPP, HMBPP, HO-DMAPP
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关于此项目
经验公式（希尔记法）:
C5H12O8P2 · xLi+
化学文摘社编号:
分子量:
262.09 (free acid basis)
MDL number:
UNSPSC Code:
12352302
NACRES:
NA.85
Assay:
≥95.0% (TLC)
Form:
solid
产品名称
(E)-1-羟基-2-甲基-2-丁烯基4-焦磷酸酯 锂盐, ≥95.0% (TLC)
SMILES string
[P](=O)([O-])([O-])O[P](=O)([O-])OCC=C(CO)C
InChI
1S/C5H12O8P2/c1-5(4-6)2-3-12-15(10,11)13-14(7,8)9/h2,6H,3-4H2,1H3,(H,10,11)(H2,7,8,9)/p-3
InChI key
MDSIZRKJVDMQOQ-UHFFFAOYSA-K
assay
≥95.0% (TLC)
form
solid
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
HMB-PP是类异戊二烯生物合成的非甲羟戊酸途径（MEP途径）的一种中间体；它被证明是一种有效的γδT细胞激活剂。
Packaging
无底玻璃瓶。内含物装在插入的融合锥内。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Matthias Eberl et al.
FEBS letters, 544(1-3), 4-10 (2003-06-05)
Human Vgamma9/Vdelta2 T cells play a crucial role in the immune response to microbial pathogens, yet their unconventional reactivity towards non-peptide antigens has been enigmatic until recently. The break-through in identification of the specific activator was only possible due to
Felix Rohdich et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(3), 1158-1163 (2002-01-31)
Isopentenyl diphosphate and dimethylallyl diphosphate serve as the universal precursors for the biosynthesis of terpenes. Although their biosynthesis by means of mevalonate has been studied in detail, a second biosynthetic pathway for their formation by means of 1-deoxy-D-xylulose 5-phosphate has
M Hintz et al.
FEBS letters, 509(2), 317-322 (2001-12-14)
The gcpE and lytB gene products control the terminal steps of isoprenoid biosynthesis via the 2-C-methyl-D-erythritol 4-phosphate pathway in Escherichia coli. In lytB-deficient mutants, a highly immunogenic compound accumulates significantly, compared to wild-type E. coli, but is apparently absent in
The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants.
M Rohmer
Natural product reports, 16(5), 565-574 (1999-12-10)
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