L5647
利多卡因 盐酸盐 一水合物
≥99% (HPLC), solid, Na⁺ channel blocker
别名:
2-二乙氨基-N-（2，6-二甲苯基）乙酰胺 盐酸盐 一水合物, 利多卡因 盐酸盐 一水合物, 赛洛卡因 盐酸盐 一水合物
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关于此项目
经验公式（希尔记法）:
C14H22N2O · HCl · H2O
化学文摘社编号:
分子量:
288.81
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-803-8
MDL number:
产品名称
利多卡因 盐酸盐 一水合物, solid
InChI
1S/C14H22N2O.ClH.H2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H;1H2
InChI key
YECIFGHRMFEPJK-UHFFFAOYSA-N
SMILES string
Cl[H].[H]O[H].CCN(CC)CC(=O)Nc1c(C)cccc1C
form
solid
color
white
solubility
H2O: soluble
Quality Level
Gene Information
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相关类别
Biochem/physiol Actions
Na+ 通道阻滞剂；IB 类抗心律失常药，在肠胃外给药后迅速吸收
Na+ 通道阻滞剂；IB 类抗心律失常药。
Application
Lidocaine hydrochloride monohydrate has been used:
- in the preparation of drug composite for the controlled delivery in vitro, evaluated by drug release profile in ultra-high performance liquid chromatography (UPLC) and as a reference standard for fourier transform infrared spectroscopy (FT-IR).
- to record dose dependent response of sodium voltage (Nav1.7) channels in the injection-molded polymer device.
- For inhibition of glial cells in brain tissue samples.
General description
Lidocaine hydrochloride monohydrate is a commonly used as local anesthetic in topical applications and oral mucosal biopsies. It has a short anesthetic half-life.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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