P8296
5-磷酰核糖-1-焦磷酸酶 五钠盐
≥75% (HPLC)
别名:
α-D-核糖二磷酸5-磷酸 五钠盐, 5-磷酸-α-D-核糖基二磷酸酯, 5-磷酸核糖基1-焦磷酸酯 五钠盐, P-Rib-PP, PRPP 五钠盐
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关于此项目
经验公式（希尔记法）:
C5H8Na5O14P3
化学文摘社编号:
分子量:
499.98
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6043637
Quality Level
assay
≥75% (HPLC)
form
powder
impurities
<18% water (Karl Fischer)
color
white
solubility
water: 50 mg/mL, clear to slightly hazy, colorless to very faintly yellow
shipped in
dry ice
storage temp.
−20°C
SMILES string
[Na+].[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@H](O[C@@H]1COP(O)([O-])=O)OP([O-])(=O)OP([O-])([O-])=O
InChI
1S/C5H13O14P3.4Na/c6-3-2(1-16-20(8,9)10)17-5(4(3)7)18-22(14,15)19-21(11,12)13;;;;/h2-7H,1H2,(H,14,15)(H2,8,9,10)(H2,11,12,13);;;;/q;4*+1/p-4/t2-,3-,4-,5?;;;;/m1..../s1
InChI key
QZAPPJHVNYCTAX-CKJQBBATSA-J
L D Gegnas et al.
Bioorganic & medicinal chemistry letters, 8(13), 1643-1648 (1999-01-05)
A series of transition-state analog inhibitors of the D-glutamic acid-adding enzyme (MurD) of bacterial peptidoglycan biosynthesis has been synthesized and evaluated for inhibition of the E. coli enzyme.
P Pacaud et al.
The Journal of physiology, 441, 477-499 (1991-09-01)
1. The action of carbachol, which activates muscarinic receptors, was studied in single patch-clamped cells where free internal calcium concentration in the cell (Cai2+) was estimated using the emission from the dye Indo-1. Cells were dialysed with potassium-free caesium solution
Nisreen Wahwah et al.
Scientific reports, 10(1), 19907-19907 (2020-11-18)
Cisplatin is a mainstay of cancer chemotherapy. It forms DNA adducts, thereby activating poly(ADP-ribose) polymerases (PARPs) to initiate DNA repair. The PARP substrate NAD+ is synthesized from 5-phosphoribose-1-pyrophosphate (PRPP), and we found that treating cells for 6 h with cisplatin reduced
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P8296-250MG | 04061832392677 |
| P8296-100MG | 04061834401278 |
| P8296-500MG | 04061834401292 |
| P8296-25MG | 04061834401285 |