V100
(±)-Vesamicol hydrochloride
>98%, solid
别名:
(±)-2-(4-Phenylpiperidino)cyclohexanol hydrochloride, AH-5183 hydrochloride
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关于此项目
经验公式（希尔记法）:
C17H25NO · HCl
化学文摘社编号:
分子量:
295.85
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
>98%
form
solid
color
white
solubility
aqueous buffers below pH 8: 1 mM, DMSO: soluble, ethanol: soluble
SMILES string
Cl.OC1CCCCC1N2CCC(CC2)c3ccccc3
InChI
1S/C17H25NO.ClH/c19-17-9-5-4-8-16(17)18-12-10-15(11-13-18)14-6-2-1-3-7-14;/h1-3,6-7,15-17,19H,4-5,8-13H2;1H
InChI key
XJNUHVMJVWOYCW-UHFFFAOYSA-N
Gene Information
human ... SLC18A3(6572)
Biochem/physiol Actions
Potent inhibitor of vesicular acetylcholine storage.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Mee-Rye Park et al.
ChemSusChem, 13(17), 4455-4467 (2020-03-12)
There is strong interest in the valorization of lignin to produce valuable products; however, its structural complexity has been a conversion bottleneck. Chemical pretreatment liberates lignin-derived soluble fractions that may be upgraded by bioconversion. Cholinium ionic liquid pretreatment of sorghum
The vesicular acetylcholine transport system.
Marshall,L, et al.
Trends in Neurosciences, 10, 174-174 (1987)
B A Bahr et al.
Proceedings of the National Academy of Sciences of the United States of America, 83(7), 2267-2270 (1986-04-01)
Transport and storage of acetylcholine by purified Torpedo electric organ synaptic vesicles is blocked by the drug L-trans-2-(4-phenylpiperidino)cyclohexanol (AH-5183). This study sought evidence of a specific receptor for the drug. Highly tritiated L-trans-2-(4-phenyl [3,4-3H] piperidino)-cyclohexanol (L-[3H] AH5183) was synthesized. An