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Merck
CN

A0167

Sigma-Aldrich

半乳-N-二糖

别名:

β-D-Gal-(1→3)-D-GalNAc, 2-乙酰氨基-2-脱氧-3-O-β-D-吡喃半乳糖基-D-吡喃半乳糖, T 抗原

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关于此项目

经验公式（希尔记法）:
C14H25NO11
CAS Number:
20972-29-6
分子量:
383.35
MDL编号:
MFCD00063995
UNSPSC代码:
12352201
PubChem化学物质编号:
24890406
NACRES:
NA.25

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方案

≥98% (TLC)

表单

powder

技术

thin layer chromatography (TLC): suitable

储存温度

−20°C

SMILES字符串

CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O

InChI

1S/C14H25NO11/c1-4(18)15-7-12(9(20)6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8+,9+,10+,11-,12-,13-,14+/m1/s1

InChI key

HMQPEDMEOBLSQB-UFLFEMAHSA-N

一般描述

N-乙酰葡糖胺基转移酶、岩藻糖基转移酶和唾液酸转移酶以及半乳糖苷酶的底物。也可用于凝集素抑制研究。

应用

Galacto-N-biose, a component of the galacto-N-biose/lacto-N-biose metabolic pathway, is used as a substrate to identify, differentiate and characterize enzymes such as N-acetylglucosaminyltransferase(s), fucosyl- and sialyltransferase(s), galactosidase(s) and galacto-N-biose/lacto-N-biose I phosphorylase(s) (GLNBP). Galacto-N-biose is used in lectin inhibition studies.

其他说明

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
109K5012V
110M4009V
091M4012V
087H51135
087H51134

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S E Tollefsen et al.
The Journal of biological chemistry, 258(8), 5172-5176 (1983-04-25)
We have examined the carbohydrate binding specificity of the B4 lectin from Vicia villosa seeds. The B4 lectin agglutinates Tn-exposed erythrocytes specifically and binds to these erythrocytes (1.4 X 10(6) sites/cell) with an association constant of 4.2 X 10(7) M-1.
T A Beyer et al.
The Journal of biological chemistry, 255(11), 5373-5379 (1980-06-10)
The acceptor substrate specificity and kinetic properties of the purified porcine submaxillary beta-galactoside alpha 1 leads to 2 fucosyltransferase have been examined. The transferase forms the Fuc alpha 1 leads to 2Gal linkage with oligosaccharides, glycoproteins, and glycolipids which contain
D Williams et al.
The Journal of biological chemistry, 255(23), 11253-11261 (1980-12-10)
The preceding paper (Williams, D., and Schachter, H. (1980) J. Biol. Chem. 255, 0000-0000) described a novel N-acetylglucosaminyltransferase in canine submaxillary gland microsomes which catalyzed the incorporation of GlcNAc into mucin acceptors. We show in the present report that the
J I Rearick et al.
The Journal of biological chemistry, 254(11), 4444-4451 (1979-06-10)
The substrate requirements, linkage specificity, and kinetic mechanism of a pure sialyltransferase from porcine submaxillary glands have been examined. The enzyme transfers sialic acid from the donor nucleotide, CMP-NeuAc, into the sequence NeuAcalpha2 leads to 3Galbeta1 leads to 3GalNAc, which
D M Moujalled et al.
Cell death & disease, 4, e465-e465 (2013-01-19)
Ligation of tumor necrosis factor receptor 1 (TNFR1) can cause cell death by caspase 8 or receptor-interacting protein kinase 1 (RIPK1)- and RIPK3-dependent mechanisms. It has been assumed that because RIPK1 bears a death domain (DD), but RIPK3 does not
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商品

Review of O-Linked Glycoproteins

O-Linked glycoproteins are usually large proteins with a molecular mass of >200 kDa. Glycosylation generally occurs in high-density clusters and may represent as much as 50-80% of the overall mass.

O-连接糖蛋白回顾

O-连接糖蛋白通常是分子量>200kDa的大蛋白。糖基化通常发生在高密度簇上，并可占总量的50-80%。

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