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Merck
CN

A0189

Amyloid β Protein Fragment 1-38

≥95% (HPLC), powder

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关于此项目

经验公式(希尔记法):
C184H277N51O56S
化学文摘社编号:
分子量:
4131.54
UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:
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产品名称

Amyloid β Protein Fragment 1-38, ≥95% (HPLC), powder

assay

≥95% (HPLC)

form

powder

color

white

solubility

H2O: 1 mg/mL

UniProt accession no.

storage temp.

−20°C

Quality Level

Gene Information

human ... APP(351)

Biochem/physiol Actions

β-Amyloid peptide that forms cross-β-sheet fibrils of 70-90 Å diameter with similar antigenicity as those found in Alzheimer′s disease.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M P Mattson et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 12(2), 376-389 (1992-02-01)
In Alzheimer's disease (AD), abnormal accumulations of beta-amyloid are present in the brain and degenerating neurons exhibit cytoskeletal aberrations (neurofibrillary tangles). Roles for beta-amyloid in the neuronal degeneration of AD have been suggested based on recent data obtained in rodent
P E Fraser et al.
Journal of neuroscience research, 28(4), 474-485 (1991-04-01)
To elucidate the relationship between amyloid fibril formation in Alzheimer disease (AD) and the primary structure of the beta-amyloid protein (beta-AP), we investigated the ability of peptides sharing sequences with beta-AP to form fibrils in vitro and to recognize anti-beta-amyloid
P E Gottschall
Neuroreport, 7(18), 3077-3080 (1996-11-25)
Since administration of anti-inflammatory drugs has been reported to possibly slow the progression of Alzheimer's disease, an effort was made to define effector functions induced by beta-amyloid (A beta) which may be inhibited by these drugs. Rat microglia in culture

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