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About This Item
经验公式(希尔记法):
C6H16N6 · H2O4S
CAS Number:
分子量:
270.31
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
生物来源
synthetic (organic)
质量水平
方案
≥98% (TLC)
表单
powder
mp
>280 °C
溶解性
1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
SMILES字符串
OS(O)(=O)=O.NC(=N)NCCCCNC(N)=N
InChI
1S/C6H16N6.H2O4S/c7-5(8)11-3-1-2-4-12-6(9)10;1-5(2,3)4/h1-4H2,(H4,7,8,11)(H4,9,10,12);(H2,1,2,3,4)
InChI key
RWTGFMPOODRXIM-UHFFFAOYSA-N
基因信息
human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)
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应用
Arcaine sulfate salt has been used as an N-methyl-d-aspartate (NMDA) receptor effector/antagonist:
- to evaluate its effects on the acquisition of electrical kindling of the amygdala
- to compare its effects with agmatine and MK801 on NMDA- or glutamate-induced neuronal damage
- to study its effects on cell-free translation of synthetic polynucleotide
生化/生理作用
Arcaine sulfate salt (1,4-diguanidinobutane), a polyamine, is an antagonist of the polyamine binding site of the N-methyl-d-aspartate (NMDA) receptor. Arcaine, an agmatine analog, along with ifenprodil, might have a possibility for therapeutic management in epileptic disorders.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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