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Merck
CN

A0781

Aphidicolin from Nigrospora sphaerica

≥98% (HPLC), DNA polymerase inhibitor, powder

别名:

APC

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经验公式（希尔记法）:
C20H34O4
化学文摘社编号:
38966-21-1
分子量:
338.48
Beilstein:
4689958
MDL编号:
MFCD00083214
UNSPSC代码:
12352200
PubChem化学物质编号:
57653817
NACRES:
NA.77

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产品名称

Aphidicolin from Nigrospora sphaerica, ≥98% (HPLC), powder

质量水平

300

方案

≥98% (HPLC)

表单

powder

旋光性

[α]27/D +12°, c = 1 in methanol(lit.)

颜色

white

mp

227-233 °C (lit.)

溶解性

ethanol: 1 mg/mL (stable at least a week at 4°C.)
DMSO: 10 mg/mL (stable at least six weeks at −20°C.)
methanol: 10 mg/mL
H2O: insoluble

抗生素抗菌谱

neoplastics
viruses

作用机制

DNA synthesis | interferes

储存温度

2-8°C

SMILES字符串

[H][C@@]12CC[C@@]3([H])[C@](C)(CO)[C@H](O)CC[C@]3(C)[C@]14CC[C@](O)(CO)[C@]([H])(C2)C4

InChI

1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1

InChI key

NOFOAYPPHIUXJR-APNQCZIXSA-N

基因信息

human ... POLA1(5422), POLD1(5424), POLG(5428)

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相关类别

生化/生理作用

Aphidicolin is an antibiotic, a potent antiviral and antimitotic agent and DNA polymerase inhibitor.

特点和优势

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

免责声明

Estimated shelf-life is two years. For optimal stability, it should be protected from light and stored desiccated.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000477736
0000477736
0000447995
0000447995
0000453980

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Apoptosis regulation involves multiple pathways and molecules for cellular homeostasis.

Discover Bioactive Small Molecules for Cell Cycle

Cell cycle phases (G1, S, G2, M) regulate cell growth, DNA replication, and division in proliferating cells.

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