A1164
偶氮丝氨酸
Hybri-Max™, γ-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma
别名:
O-重氮乙酰基-L-丝氨酸
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关于此项目
经验公式（希尔记法）:
C5H7N3O4
化学文摘社编号:
分子量:
173.13
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
EC Number:
204-061-6
Beilstein/REAXYS Number:
1726602
MDL number:
grade
Hybri-Max™
Quality Level
sterility
γ-irradiated
product line
BioXtra
form
lyophilized powder
technique(s)
cell culture | hybridoma: suitable
impurities
endotoxin, tested
antibiotic activity spectrum
fungi
mode of action
enzyme | inhibits
storage temp.
−20°C
SMILES string
N[C@@H](COC(=O)C=[N+]=[N-])C(O)=O
InChI
1S/C5H7N3O4/c6-3(5(10)11)2-12-4(9)1-8-7/h1,3H,2,6H2,(H,10,11)/t3-/m0/s1
InChI key
MZZGOOYMKKIOOX-VKHMYHEASA-N
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General description
Chemical structure: amino acid derivatives
Application
For use in hybridoma cell culture applications as a myeloma selection agent. Used to study inhibition of formylglycinamide ribonucleotide amidotransferase and PRPP amidotransferase.
Biochem/physiol Actions
Azaserine is an antibiotic, generated by Streptomyces fragilis. It is considered as a potential mutation inducing agent. It is known to promote pancreatic cancer and induces adenoma and carcinoma in vivo and in vitro. Azaserine also stimulates kidney and liver tumors in rats.
Preparation Note
10mL 无菌细胞培养基可复原一小瓶本品。储备液足以制备 500mL 培养基。最终工作浓度：5.7μM 偶氮丝氨酸。
Legal Information
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Carc. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
Antineoplastic and Immunosuppressive Agents, Part 2, 494-494 (2013)
Christiane Bierkamp et al.
The American journal of pathology, 165(6), 2135-2145 (2004-12-08)
The presence of gastrin and cholecystokinin-2 (CCK2) receptors in human preneoplastic and neoplastic gastrointestinal lesions suggests a role in cancer development. In addition to the growth-promoting action of gastrin, recently a role of the cholecystokinin-2/gastrin receptor (CCK2-R) modulating cellular morphology
Kirsten Bagh et al.
Plant physiology and biochemistry : PPB, 42(10), 803-809 (2004-12-15)
In vivo (15)N nuclear magnetic resonance (NMR) as well as (15)N solid-state magic angle spinning (MAS) NMR spectroscopy were used to investigate nitrogen metabolism in cultured white spruce (Picea glauca) buds. Long-term as well as short-term experiments were carried out
Marie Pantaleon et al.
Biology of reproduction, 78(4), 595-600 (2007-11-30)
Although mouse oocytes and cleavage-stage embryos are unable to utilize glucose as a metabolic fuel, they have a specific requirement for a short exposure to glucose prior to compaction. The reason for this requirement has been unclear. In this study
A J Almeida et al.
Fungal genetics and biology : FG & B, 44(12), 1387-1398 (2007-05-22)
We herein report the development of a molecular toolbox for the dimorphic fungus Paracoccidioides brasiliensis, specifically a more efficient transformation and a gene expression system. We evaluated several parameters that influence Agrobacterium tumefaciens-mediated transformation (ATMT), such as co-cultivation conditions and
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A1164-.5MG | 04061833341926 |
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