A1355
Anti-Archvillin antibody produced in rabbit
~1 mg/mL, affinity isolated antibody, PBS solution
别名:
Anti-SVIL, Anti-Supervillin (p205/p250), Anti-Supervillin isoform 2, SmAV (Smooth muscle Archvillin)
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC (p), WB
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
PBS solution
mol wt
antigen ~250 kDa
species reactivity
rat, mouse, human
concentration
~1 mg/mL
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 20-40 μg/mL using heat-retrieved tissue sections from human heart by biotin/ExtrAvidin-Peroxidase, indirect immunofluorescence: 20-40 μg/mL using differentiated rat L8 cells, western blot: 2.5-5 μg/mL using whole extract of differentiated mouse C2 cells
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SVIL(6840)
mouse ... Svil(225115)
rat ... Svil(361256)
General description
Archvillin is a muscle-specific isoform of Supervillin. Archvillin binds F-actin and is believed to be involved in myogenesis and muscle cell migration. Archvillin binds ERK and modulates ERK signaling in smooth cells of the aortas of ferrets.
Rabbit anti-archvillin antibody binds to human, mouse, and rat archvillin.
Immunogen
synthetic peptide corresponding to amino acid residues 650-666 of human archvillin. The corresponding sequence is identical in mouse.
Application
Rabbit anti-archvillin antibody can be used for immunohistochemistry at 20-40 μg/mL using heat-retrieved tissue sections from human heart by biotin/ExtrAvidin-Peroxidase. The antibody can also be used for indirect immunofluorescence at 20-40 μg/mL using differentiated rat L8 cells. Furthermore, the antibody is suitable for use in western blot (2.5-5 μg/mL using whole extract of differentiated mouse C2 cells) assays.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable