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Merck
CN

A1472

MCA-[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676-DNP-Lys-Arg-Arg-NH2

≥90% (HPLC)

别名:

7-Methoxycoumarin-4-acetyl-[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676(2,4-dinitrophenyl)Lys-Arg-Arg amide

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关于此项目

经验公式(希尔记法):
C86H125N27O29
分子量:
2001.08
UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
Assay:
≥90% (HPLC)
Form:
powder
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Quality Segment

assay

≥90% (HPLC)

form

powder

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... APP(351)

Application

7-Methoxycoumarin-4-acetyl-[Asn⁶⁷⁰,Leu⁶⁷¹]-Amyloid β has been used as a fluorogenic substrate to measure β-secretase activity.

Biochem/physiol Actions

Fluorescent peptide substrate containing the ′Swedish′ Lys-Met/Asn-Leu mutation of the amyloid presursor protein (APP) β-secretase cleavage site. May be used for assaying β-secretase-like activity of thimet oligopeptidase (TOP), EC 3.4.24.15.
Fluorescent peptide substrate with the ′Swedish′ Lys-Met/Asn-Leu mutation of amyloid presursor protein (APP) β-secretase cleavage site.


存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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