A1479
Angiopoietin-4 human
recombinant, expressed in NSO cells, ≥85% (SDS-PAGE), lyophilized powder
别名:
ANG-4
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关于此项目
UNSPSC Code:
51111800
MDL number:
Form:
lyophilized powder
Assay:
≥85% (SDS-PAGE)
Biological source:
human
Recombinant:
expressed in NSO cells
Mol wt:
apparent mol wt 60-100 kDa by SDS-PAGE (reducing)
calculated mol wt 57 kDa
calculated mol wt 57 kDa
产品名称
Angiopoietin-4 human, recombinant, expressed in NSO cells, ≥85% (SDS-PAGE), lyophilized powder
biological source
human
recombinant
expressed in NSO cells
assay
≥85% (SDS-PAGE)
form
lyophilized powder
mol wt
apparent mol wt 60-100 kDa by SDS-PAGE (reducing)
calculated mol wt 57 kDa
storage condition
avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... ANGPT4(51378)
Analysis Note
The biological activity is measured by its ability to compete with biotinylated recombinant human ANG-2 for binding to immobilized Tie-2/Fc in an ELISA.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline, pH 6.8, containing 1.25 mg bovine serum albumin.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
胰岛素激素类产品
此项目有
Spencer B Mamer et al.
Scientific reports, 7(1), 16439-16439 (2017-11-29)
Nearly all studies of angiogenesis have focused on uni-family ligand-receptor binding, e.g., VEGFs bind to VEGF receptors, PDGFs bind to PDGF receptors, etc. The discovery of VEGF-PDGFRs binding challenges this paradigm and calls for investigation of other ligand-receptor binding possibilities.
M Nishimura et al.
FEBS letters, 448(2-3), 254-256 (1999-04-28)
A cDNA clone encoding angiopoietin-3 protein (Ang3), a novel member of the angiopoietin family, was identified. Ang3 cDNA was cloned from a human aorta cDNA library. Ang3 is a 503 amino acid protein having 45.1% and 44.7% identity with human
D M Valenzuela et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(5), 1904-1909 (1999-03-03)
The angiopoietins have recently joined the members of the vascular endothelial growth factor family as the only known growth factors largely specific for vascular endothelium. The angiopoietins include a naturally occurring agonist, angiopoietin-1, as well as a naturally occurring antagonist
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