A1632
DL-7-Azatryptophan hydrate
≥98% (TLC)
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关于此项目
经验公式（希尔记法）:
C10H11N3O2 · H2O
化学文摘社编号:
分子量:
223.23
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
产品名称
DL-7-Azatryptophan hydrate,
SMILES string
O.NC(Cc1c[nH]c2ncccc12)C(O)=O
InChI
1S/C10H11N3O2.H2O/c11-8(10(14)15)4-6-5-13-9-7(6)2-1-3-12-9;/h1-3,5,8H,4,11H2,(H,12,13)(H,14,15);1H2
InChI key
PXDRHYQAIUZKHN-UHFFFAOYSA-N
assay
≥98% (TLC)
form
powder
color
white to off-white
storage temp.
−20°C
Biochem/physiol Actions
DL-7-Azatryptophan is a racemic mixture of D- and L-7-azatryptophan which together with L-tryptophan is a synergistic inducer of tryptophan oxygenase of Pseudomonas acidovorans. DL-7-Azatryptophan inhibits photosynthetic carbon assimilation, photosynthetic oxygen evolution and nitrogen metabolism in Anabaena sp. Strain 1F, a marine filamentous, heterocystous cyanobacterium.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
J Guharay et al.
Biochemical and biophysical research communications, 219(2), 388-392 (1996-02-15)
The amino acid analogue 7-azatryptophan has attracted significant recent attention as a novel optical probe for protein structure, function and dynamics. We report here, for the first time, its fluorescence emission behavior in a membrane mimetic model system, namely reverse
Lars Merkel et al.
Chembiochem : a European journal of chemical biology, 11(3), 305-314 (2010-01-09)
In vivo expression of colored proteins without post-translational modification or chemical functionalization is highly desired for protein studies and cell biology. Cell-permeable tryptophan analogues, such as azatryptophans, have proved to be almost ideal isosteric substitutes for natural tryptophan in cellular
C W Hogue et al.
Biophysical chemistry, 48(2), 159-169 (1993-12-01)
The tryptophan analogs 5-hydroxytryptophan (5HW) and 7-azatryptophan (7AW) are capable of being biosynthetically incorporated into bacterial proteins and can be used as intrinsic fluorescence probes of protein structure, function and dynamics. A prerequisite for analog incorporation is their recognition by
Michael Georg Hoesl et al.
Journal of peptide science : an official publication of the European Peptide Society, 16(10), 589-595 (2010-07-16)
Aequorea victoria green fluorescent protein and its widely used mutants enhanced green fluorescent protein and enhanced cyan fluorescent protein (ECFP) are ideal target proteins to study protein folding. The spectral signals of their chromophores are directly correlated with the folding
C H Chen et al.
Journal of bacteriology, 169(3), 1114-1119 (1987-03-01)
An alternative route for the primary assimilation of ammonia proceeds via glutamine synthetase-carbamyl phosphate synthetase and its inherent glutaminase activity in Anabaena sp. strain 1F, a marine filamentous, heterocystous cyanobacterium. Evidence for the presence of this possible alternative route to
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