A165
Rp-腺苷 3′，5′-环状单硫代磷酸酯 三乙铵盐
≥98% (HPLC), cAMP antagonist, powder
别名:
Rp-cAMPS 三乙铵盐, Rp-环状 3′，5′-氢硫代磷酸酯腺苷 三乙铵盐
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关于此项目
经验公式（希尔记法）:
C10H11N5O5PS · C6H16N
化学文摘社编号:
分子量:
446.46
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
Rp-腺苷 3′，5′-环状单硫代磷酸酯 三乙铵盐, powder, ≥98% (HPLC)
SMILES string
CCN(CC)CC.Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP(O)(=S)O[C@H]4[C@H]3O
InChI
1S/C10H12N5O5PS.C6H15N/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(19-10)1-18-21(17,22)20-7;1-4-7(5-2)6-3/h2-4,6-7,10,16H,1H2,(H,17,22)(H2,11,12,13);4-6H2,1-3H3/t4-,6-,7-,10-,21?;/m1./s1
InChI key
OXIPZMKSNMRTIV-NVGWRVNNSA-N
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 10 mg/mL
λmax
258 nm
storage temp.
−20°C
Quality Level
相关类别
Application
Rp-腺苷-3′，5′-环一硫代磷酸三乙酯铵盐已被用作cAMP的拮抗剂，以阻断cAMP-PKA信号通路。
Biochem/physiol Actions
Rp-腺苷-3′，5′-环一硫代磷酸三乙酯铵盐能够抑制蛋白激酶A（PKA）。
腺苷-3′，5′-环状单硫代磷酸酯 Rp-非对映异构体。cAMP（cAMP 依赖性蛋白激酶I 和 II）激活作用的特异性膜渗透性抑制剂；对环核苷酸磷酸二酯酶具有抗性；在许多系统中阻断 cAMP 介导的作用。
Disclaimer
非常吸湿。储存于干燥处。
Features and Benefits
这种化合物是环核苷酸研究的特色产品。点击此处发现更多特色环核苷酸产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
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商品
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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