A1852
腺苷 5′-三磷酸腺苷 (ATP) 二钠盐 水合物
≥99% (HPLC), microbial (Corynebacterium sp.), powder
别名:
ATP 二钠 水合物
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关于此项目
线性分子式:
C10H14N5O13P3Na2 · xH2O
化学文摘社编号:
分子量:
551.14 (anhydrous basis)
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
EC Number:
213-579-1
NACRES:
NA.51
MDL number:
产品名称
腺苷 5′-三磷酸腺苷 (ATP) 二钠盐 水合物, vial of 30 mg
SMILES string
Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
InChI key
NTBQNWBHIXNPRU-MSQVLRTGSA-L
InChI
1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
biological source
microbial (Corynebacterium sp.)
assay
≥99% (HPLC)
form
powder
packaging
vial of 30 mg
solubility
water: 50 mg/mL, clear, colorless
storage temp.
−20°C
Quality Level
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Application
5′-三磷酸腺苷（ATP）二钠盐水合物用于：
- 在大鼠海马切片培养物中模拟突触信号传导
- 从原代猪肺泡巨噬细胞（PAM）中分离质粒
- 用作热反应激酶缓冲液的成分，用于凝胶激酶检测
ATP是许多酶反应中的辅酶。腺苷5′-三磷酸 (ATP) 二钠盐水合物用于组织制备和维护。
Biochem/physiol Actions
P2 嘌呤能激动剂；增加 Ca2+-激活的 K+ 通道的活性；ATP-依赖酶系统的底物
General description
腺苷5γ-三磷酸(ATP)是体内能量储存和代谢的核心组分。 ATP用于许多细胞过程，呼吸，生物合成反应，移动和细胞分裂。ATP是许多细胞信号激酶和腺苷酸环化酶产生二级信使CAMP的底物。 ATP为驱动代谢泵提供代谢能。
存储类别
11 - Combustible Solids
wgk
WGK 2
ppe
Eyeshields, Gloves, type N95 (US)
Mark D A van Logtestijn et al.
PloS one, 10(2), e0117292-e0117292 (2015-02-12)
The stratum corneum (SC) provides a permeability barrier that limits the inflow and outflow of water. The permeability barrier is continuously and dynamically formed, maintained, and degraded along the depth, from the bottom to the top, of the SC. Naturally
Bio-Protocol
Pizzio GA and Rodriguez PL
Testing, 7(5) (2017)
NS1 protein of 2009 pandemic influenza A virus inhibits porcine NLRP3 inflammasome-mediated interleukin-1 beta production by suppressing ASC ubiquitination
Park HS, et al.
Journal of Virology, JVI-00022 (2018)
JuanJuan Duan et al.
Cellular signalling, 58, 44-52 (2019-03-12)
Persistent inflammasome activation contributes to chronic, low grade inflammation. However, it is unclear how the inflammasome activation is sustained after initiation. Here we reported that N4-acetylcytidine (N4A), a nucleoside metabolite, activated microglia and sustained NLRP3 inflammasome activation by inducing HMGB1
Stephani Velasquez et al.
EBioMedicine, 51, 102503-102503 (2019-12-07)
In developed countries, Human Immunodeficiency Virus type-1 (HIV-1) infection has become a chronic disease despite the positive effects of anti-retroviral therapies (ART), but still at least half of the HIV infected population shown signs of cognitive impairment. Therefore, biomarkers of
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