跳转至内容

主要文件

查看所有文档

A1908

Asialofetuin 来源于胎牛血清

Type II (Sigma designation)

登录并加购，请在购物车里查看协议价、货期和发货地。

选择规格

变更视图

关于此项目

UNSPSC Code:
12352202
NACRES:
NA.61
MDL number:
MFCD00130561
Form:
powder
Biological source:
bovine
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

biological source

bovine

Quality Segment

200

type

Type II (Sigma designation)

form

powder

technique(s)

activity assay: suitable, inhibition assay: suitable

impurities

salt, essentially free, ≤1.0% N-acetylneuraminic acid

solubility

H2O: soluble 1.0 mg/mL, clear to hazy, colorless to very faintly yellow

storage temp.

2-8°C

Application

Asialofetuin from fetal calf serum is suitable for use:
  • in the assay of the lactose binding activity of the galectin-7 by immunodetection of in situ binding activity to asialofetuin immobilized on nitrocellulose
  • in the inhibition of zona pellucida hardening of mouse oocytes
  • as an acceptor in sialyltransferase enzyme activity assay
Incorporation of asialofetuin (AF) in liposomes strongly enhance delivery to and endocytosis by cells displaying the AF receptor, notably hepatocytes. This provides a very efficient route for gene therapy.

Biochem/physiol Actions

Asialofetuin (AF) binds to asialoglycoprotein receptor (ASGP-R) and is employed as a ligand for drug delivery to the hepatocytes. It aids serum-resistant lipoplexes for efficient gene deliver into the HepG2 (human hepatoblastoma) cells.
Feutins are glycoproteins that belong to the cystatin superfamily. They are characterized by the presence of two tandemly arranged cystatin-like domains and an unrelated domain. It binds to transforming growth factor (TGF)-β/BMP (bone morphogenic protein) cytokines.

Preparation Note

Enzymatic cleavage using neuraminidase

Still not finding the right product?

Explore all of our products under Asialofetuin 来源于胎牛血清

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库