A2010
Nα-乙酰基-L-赖氨酸
≥98% (TLC), suitable for ligand binding assays
别名:
N2-acetyl-L-lysine
Product Name
Nα-乙酰基-L-赖氨酸,
方案
≥98% (TLC)
质量水平
表单
powder
技术
ligand binding assay: suitable
颜色
colorless to white
mp
256-258 °C (dec.) (lit.)
储存温度
−20°C
SMILES字符串
CC(=O)N[C@@H](CCCCN)C(O)=O
InChI
1S/C8H16N2O3/c1-6(11)10-7(8(12)13)4-2-3-5-9/h7H,2-5,9H2,1H3,(H,10,11)(H,12,13)/t7-/m0/s1
InChI key
VEYYWZRYIYDQJM-ZETCQYMHSA-N
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相关类别
应用
Nα-乙酰基L-赖氨酸已作为赖氨酰氧化酶的底物，用于合成真正的α-氨基己二酸半醛 (AAS)-p-氨基苯甲酸 (ABA)。它可用于合成4,4′-亚甲基二苯基二异氰酸酯 (MDI) 的氨基酸加成物。
生化/生理作用
Nα-乙酰基-L-赖氨酸是蛋白质原型α氨基酸L-赖氨酸的一种生物学上可获得的N-末端封端形式。Nα-乙酰基-L-赖氨酸是用于研究和表征赖氨酰氧化酶的一种底物。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
K Seyssel et al.
The Journal of clinical endocrinology and metabolism, 99(7), E1254-E1262 (2014-04-02)
The aim of this study was to evaluate the regulation of the fuel partitioning and energy metabolism in skeletal muscle during lipid overfeeding in healthy men. Design/Participants/Intervention: Thirty-nine healthy volunteers were overfed for 56 days with a high-fat diet (3180
Yael Belo et al.
Biochimica et biophysica acta. General subjects, 1863(9), 1343-1350 (2019-06-07)
The signal transducer and activator of transcription 3 (STAT3) protein is activated by phosphorylation of a specific tyrosine residue (Tyr705) in response to various extracellular signals. STAT3 activity was also found to be regulated by acetylation of Lys685. However, the
Wenhui Ren et al.
Scientific reports, 7, 39986-39986 (2017-01-04)
As members of bromodomain and extra-terminal motif protein family, bromodomain-containing proteins regulate a wide range of biological processes including protein scaffolding, mitosis, cell cycle progression and transcriptional regulation. The function of these bromodomain proteins (Brds) in innate immune response has
Jing Bi et al.
Emerging microbes & infections, 7(1), 108-108 (2018-06-15)
The DosR regulon is believed to be a key factor in latency adaptation of Mycobacterium tuberculosis and is strongly induced by multiple stresses, including hypoxia. Previous studies have revealed reversible acetylation of the conserved core DNA-binding lysine residue 182 (K182)
Yoshihiro Nakamura et al.
The Journal of biological chemistry, 282(6), 4193-4201 (2006-12-07)
The BET (bromodomains and extra terminal domain) family proteins recognize acetylated chromatin through their bromodomain and act as transcriptional activators. One of the BET proteins, BRD2, associates with the transcription factor E2F, the mediator components CDK8 and TRAP220, and RNA
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