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关于此项目
经验公式(希尔记法):
C18H22N6O4
化学文摘社编号:
分子量:
386.41
UNSPSC Code:
12352202
PubChem Substance ID:
MDL number:
产品名称
N6-2-(4-氨基苯基)乙基腺苷, >95%
InChI
1S/C18H22N6O4/c19-11-3-1-10(2-4-11)5-6-20-16-13-17(22-8-21-16)24(9-23-13)18-15(27)14(26)12(7-25)28-18/h1-4,8-9,12,14-15,18,25-27H,5-7,19H2,(H,20,21,22)/t12-,14-,15-,18-/m1/s1
SMILES string
Nc1ccc(CCNc2ncnc3n(cnc23)[C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O)cc1
InChI key
XTPOZVLRZZIEBW-SCFUHWHPSA-N
assay
>95%
form
solid
solubility
methanol: slightly soluble 0.2 mg/mL
0.1 M HCl: 14 mg/mL
DMSO: soluble
H2O: insoluble
storage temp.
2-8°C
Gene Information
human ... ADORA3(140)
rat ... Adora1(29290), Adora2a(25369), Adora3(25370)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
M G Collis et al.
Trends in pharmacological sciences, 14(10), 360-366 (1993-10-01)
The numerous and widespread effects of adenosine provide both an opportunity for the development of novel therapeutic agents acting via adenosine receptors and the challenge of achieving selectivity of action. The feasibility of achieving selectivity is enhanced if receptor subtypes
J R Fozard et al.
British journal of pharmacology, 109(1), 3-5 (1993-05-01)
The cardiovascular effects of N6-2-(4-aminophenyl)ethyladenosine (APNEA), which when radiolabelled with 125I shows high affinity for the newly described adenosine A3 receptor, have been investigated in the angiotensin II-supported circulation of the pithed rat. APNEA induces hypotensive responses which are unaffected
Adenosine A3 receptors: two into one won't go.
A M Carruthers et al.
Trends in pharmacological sciences, 14(8), 290-291 (1993-08-01)
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