推荐产品
生物来源
non-animal source (no BSE/TSE risk)
质量水平
产品线
Proligo Reagents
检测方案
≥99% (31P-NMR)
≥99.0% (reversed phase HPLC)
形式
powder
技术
oligo synthesis: suitable
杂质
≤0.3% water content (Karl Fischer)
≤0.5% P(III) Impurities 100-169ppm (31P-NMR)
≤0.5% single Impurity (reversed phase HPLC)
≤3% residual Solvent content
颜色
white to off-white
λ
conforms (UV/VIS Identity)
适用性
conforms to structure for H-NMR
conforms to structure for LC-MS
相容性
configured for MerMade
核苷分析
base: adenosine
base protecting group: benzoyl
2' protecting group: TBDMS
5' protecting group: DMT
deprotection: standard
储存温度
−20°C
SMILES字符串
COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4c(NC(=O)c5ccccc5)ncnc34)(c6ccccc6)c7ccc(OC)cc7
InChI
1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-46-44(33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41)66-51(47(46)68-70(10,11)52(5,6)7)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s1
InChI key
FFXHNCNNHASXCT-RFMFGJHUSA-N
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一般描述
- Industry-standard 2′O-TBDMS protective group
- Consistent lot-to-lot purity and performance
- Compatible with deprotection methods based on methylamine or AMA
- Standard RNA phosphoramidites provide excellent coupling results whenused with ETT or BTT as an activator; best results are obtained withActivator 42®
- Capping with standard acetic anhydride capping reagent rather than withFast Deprotection Cap A
- Manufactured under a certified ISO 9001 quality systemDMT-2′O-TBDMS-rA(bz) Phosphoramidite is configured for MerMade Synthesizers.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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