A2145
Acridine hydrochloride
别名:
Acridine monohydrochloride, Acridinium chloride, acridin-10-ium chloride
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关于此项目
经验公式（希尔记法）:
C13H9N · HCl
化学文摘社编号:
分子量:
215.68
EC Number:
241-762-6
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
3697519
MDL number:
mp
250-255 °C (dec.)
solubility
H2O: soluble, methanol: soluble
SMILES string
Cl[H].c1ccc2nc3ccccc3cc2c1
InChI
1S/C13H9N.ClH/c1-3-7-12-10(5-1)9-11-6-2-4-8-13(11)14-12;/h1-9H;1H
InChI key
XUESTGHCVFYOLL-UHFFFAOYSA-N
Application
Acridine hydrochloride is a fluorescent compound with λexcitation and λemission of 355 nm and 440 nm, respectively. To investigate the release properties of multilayer nanocapsules, acridine hydrochloride has been utilized as a hydrophilic drug model and was loaded into the nano-structures .
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
target_organs
Respiratory system
法规信息
新产品
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Yueheng Wu et al.
Orphanet journal of rare diseases, 15(1), 101-101 (2020-04-24)
Rubinstein-Taybi syndrome (RTS) is a rare, congenital, plurimalformative, and neurodevelopmental disorder. Previous studies have reported that large deletions contribute to more severe RTS phenotypes than those caused by CREBBP point mutations, suggesting a concurrent pathogenetic role of flanking genes, typical
Xue Gao et al.
Journal of medical genetics, 55(5), 298-306 (2018-02-18)
Background Hereditary sensorineural hearing loss is a genetically heterogeneous disorder. Objectives This study was designed to explore the genetic etiology of deafness in a large Chinese family with autosomal dominant, nonsyndromic, progressive sensorineural hearing loss (ADNSHL). Methods Whole exome sequencing
Jun Kawasaki et al.
The Journal of clinical investigation, 124(6), 2774-2784 (2014-05-20)
Vascular malformations are linked to mutations in RAS p21 protein activator 1 (RASA1, also known as p120RasGAP); however, due to the global expression of this gene, it is unclear how these mutations specifically affect the vasculature. Here, we tested the