A252
AGN 192403 hydrochloride
solid
别名:
(2-endo, 3-exo)-3-(Methylethyl)-bicyclo[2.2.1]heptan-2-amine hydrochloride
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form
solid
color
off-white
solubility
H2O: 20 mg/mL
SMILES string
Cl.CC(C)[C@@H]1[C@H]2CC[C@H](C2)[C@H]1N
Gene Information
human ... NISCH(11188)
Biochem/physiol Actions
I1 imidazoline receptor ligand.
法规信息
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Synthesis and pharmacologic evaluation of 2-endo-amino-3-exo-isopropylbicyclo[2.2.1]heptane: a potent imidazoline1 receptor specific agent.
S A Munk et al.
Journal of medicinal chemistry, 39(6), 1193-1195 (1996-03-15)
Phedias Diamandis et al.
Nature chemical biology, 3(5), 268-273 (2007-04-10)
The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways that governs the