A254
AIDA
solid
别名:
1-Amino-2,3-dihydro-1H-indene-1,5-dicarboxylic acid, 1-Aminoindan-1, 5-dicarboxylic acid, UPF 523
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C11H11NO4
化学文摘社编号:
分子量:
221.21
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
产品名称
AIDA, solid
InChI
1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16)
SMILES string
NC1(CCc2cc(ccc12)C(O)=O)C(O)=O
InChI key
LSTPKMWNRWCNLS-UHFFFAOYSA-N
form
solid
color
white
solubility
DMSO: 2 mg/mL
Quality Level
Gene Information
human ... GRM1(2911)
rat ... Grm1(24414)
正在寻找类似产品? 访问 产品对比指南
Biochem/physiol Actions
Selective mGluR1 metabotropic glutamate receptor antagonist.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Maria Joseph et al.
Molecular neurodegeneration, 12(1), 88-88 (2017-12-06)
The microtubule-associated protein Tau plays a role in neurodegeneration as well as neurogenesis. Previous work has shown that the expression of the pro-aggregant mutant Tau repeat domain causes strong aggregation and pronounced neuronal loss in the hippocampus whereas the anti-aggregant
Andreas Schuster et al.
Journal of clinical medicine, 9(1) (2020-01-17)
Background: Right ventricular (RV) function is a known predictor of adverse events in heart failure and following acute myocardial infarction (AMI). While right atrial (RA) involvement is well characterized in pulmonary arterial hypertension, its relative contributions to adverse events following
Friedrich-Christian Deuschle et al.
Theranostics, 10(5), 2172-2187 (2020-02-25)
Enhanced amino acid supply and dysregulated integrin signaling constitute two hallmarks of cancer and are pivotal for metastatic transformation of cells. In line with its function at the crossroads of both processes, overexpression of CD98hc is clinically observed in various
F Moroni et al.
The Journal of pharmacology and experimental therapeutics, 281(2), 721-729 (1997-05-01)
We examined the pharmacological profile of 1-aminoindan-1,5-dicarboxylic acid (AIDA), a rigid (carboxyphenyl)glycine derivative acting on metabotropic glutamate receptors (mGluRs). In cells transfected with mGluR1a, AIDA competitively antagonized the stimulatory responses of glutamate and (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid [(1S,3R)-ACPD] on phosphoinositide hydrolysis (pA2
Chiel C de Theije et al.
Endocrinology, 159(1), 519-534 (2017-10-27)
Hypoxemia may contribute to muscle wasting in conditions such as chronic obstructive pulmonary disease. Muscle wasting develops when muscle proteolysis exceeds protein synthesis. Hypoxia induces skeletal muscle atrophy in mice, which can in part be attributed to reduced food intake.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持