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Merck
CN

A2636

S-(2-氨基乙基)-L-半胱氨酸盐酸盐 盐酸盐

≥98% (TLC)

别名:

L-4-硫代赖氨酸 盐酸盐

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关于此项目

经验公式(希尔记法):
C5H12N2O2S · HCl
化学文摘社编号:
分子量:
200.69
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
223-862-1
MDL number:
Beilstein/REAXYS Number:
3697262
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产品名称

S-(2-氨基乙基)-L-半胱氨酸盐酸盐 盐酸盐, ≥98% (TLC)

InChI

1S/C5H12N2O2S.ClH/c6-1-2-10-3-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1

InChI key

CVHKULVNPGAEQM-WCCKRBBISA-N

SMILES string

Cl.NCCSC[C@H](N)C(O)=O

assay

≥98% (TLC)

form

powder

color

white to off-white

storage temp.

2-8°C

Quality Level

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Biochem/physiol Actions

S-(2-氨基乙基)-L-半胱氨酸(AEC)盐酸盐可作为赖氨酸类似物用于与其他赖氨酸类似物进行比较分析。S-(2-氨基乙基)-L-半胱氨酸是用于表征来自始旋链霉菌的赖氨酸环化脱氨酶的一种替代底物。AEC可用作表达赖氨酸不敏感DHPS基因的基因工程大豆的一种非抗生素选择剂。AEC正在作为一种氨基酸抗生素而被研究。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Asri Peni Wulandari et al.
FEBS letters, 522(1-3), 35-40 (2002-07-04)
In Thermus thermophilus homocitrate synthase (HCS) catalyzes the initial reaction of lysine biosynthesis through alpha-aminoadipic acid, synthesis of homocitrate from 2-oxoglutarate and acetyl-CoA. HCS is strongly inhibited by lysine, indicating that the biosynthesis is regulated by the endproduct at the
Do Youn Jun et al.
Biochemical pharmacology, 66(12), 2291-2300 (2003-11-26)
We first report the mechanism for the inhibitory effect of the lysine analog, thialysine on human acute leukemia Jurkat T cells. When Jurkat T cells were treated with thialysine (0.32-2.5 mM), apoptotic cell death along with several biochemical events such
Ulf Göransson et al.
Analytical biochemistry, 318(1), 107-117 (2003-06-05)
The expression of cyclotides-macrocyclic plant peptides-was profiled in six violets, Viola cotyledon, V. biflora, V. arvensis, V. tricolor, V. riviniana, and V. odorata, by LC-MS. All were found to express notably complex mixtures, with single species containing >50 cyclotides. To
M N Cahyanto et al.
Journal of applied microbiology, 102(3), 674-679 (2007-02-21)
To enhance L-lysine secretion in Lactobacillus plantarum. An S-2-aminoethyl-L-cystein (AEC)-resistant mutant of L. plantarum was isolated, and it produced L-lysine at considerably higher level than the parent strain. Aspartokinase in the mutant has been desensitized to feedback inhibition by L-lysine.
Dasantila Golemi-Kotra et al.
The Journal of biological chemistry, 279(33), 34665-34673 (2004-05-21)
Beta-lactamases and penicillin-binding proteins are bacterial enzymes involved in antibiotic resistance to beta-lactam antibiotics and biosynthetic assembly of cell wall, respectively. Members of these large families of enzymes all experience acylation by their respective substrates at an active site serine

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