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A2754

腺苷-5′-二磷酸 钠盐

≥95% (HPLC), bacterial, powder

别名:

ADP钠盐, ADP

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关于此项目

经验公式（希尔记法）:
C10H15N5O10P2
化学文摘社编号:
20398-34-9
分子量:
427.20
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
24890690
NACRES:
NA.51
Assay:
≥95% (HPLC)
Biological source:
bacterial
Form:
powder
Solubility:
water: 50 mg/mL, clear to hazy, colorless
Storage temp.:
−20°C
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产品名称

腺苷-5′-二磷酸 钠盐, bacterial, ≥95% (HPLC)

biological source

bacterial

Quality Level

300

assay

≥95% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear to hazy, colorless

storage temp.

−20°C

SMILES string

[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O

InChI

1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

InChI key

XTWYTFMLZFPYCI-KQYNXXCUSA-N

Gene Information

human ... HSP90AA1(3320), P2RY1(5028)

相关类别

General description

5′-二磷酸腺苷（ADP）是一种通过 FOF1-ATP 合酶转化为 ATP 而参与能量储存和核酸代谢的腺嘌呤核苷酸。ADP也可通过单磷酸腺苷酸（AMP）的腺苷酸激酶催化反应得到。ADP是一种血小板激动剂，由血小板致密颗粒分泌。它通过其与ADP受体P2Y1和P2Y12的相互作用影响血小板活化。ADP在通过ecto-ADP酶转化为腺苷后，通过腺苷受体抑制血小板活化。

Application

5′-二磷酸腺苷钠盐已用作：
  • 血小板聚集的阳性对照，用聚焦仪分析纯化解聚素的抗血小板活性。
  • 制备原液以进行线粒体应激实验。
  • 流式细胞术分析中的阳性对照品，用于研究五聚体C反应蛋白（pCRP）和单体CRP（mCRP）对血小板CD62p（P-选择素）表达的影响。
  • 血小板激动剂，刺激血小板聚集。

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000537662
0000533398
0000533405
0000533399
0000312124

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实验方案

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全球贸易项目编号

货号GTIN
A2754-100MG04061835540556
A2754-1G04061835488773
A2754-500MG04061835517602
A2754-5X1G04061835553167

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