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Merck
CN

A2853

偶氮甲烷

Practical grade, 13.4 M, ≥90% (GC)

别名:

AOM

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线性分子式:
CH3N=N(→O)CH3
化学文摘社编号:
25843-45-2
分子量:
74.08
MDL编号:
MFCD00126912
UNSPSC代码:
12352200
PubChem化学物质编号:
24890698

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方案

≥90% (GC)

质量

Practical grade

包含

≤15% ethanol and acetic acid (Packaged based on azoxymethane.)

组成

methylene chloride, ≤5%

浓度

13.4 M

沸点

97-99 °C (lit.)

密度

0.991 g/mL at 25 °C (lit.)

储存温度

−20°C

SMILES字符串

C\N=[N+](/C)[O-]

InChI

1S/C2H6N2O/c1-3-4(2)5/h1-2H3/b4-3+

InChI key

DGAKHGXRMXWHBX-ONEGZZNKSA-N

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生化/生理作用

诱导DNA中O6-甲基鸟嘌呤加合物的致癌物导致G→A转变。 在实验动物的结肠中诱导肿瘤生成，并用于研究癌症进展和化学预防的机制。

警示用语：

Danger

危险分类

Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 2 - Skin Irrit. 2

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

75.2 °F

闪点(°C)

24 °C

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
089K1157
079K1133
098K1488
098K1469
038K1557

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  1. How does the storage temperature relate to shipping conditions?

    The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.

  2. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  3. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  4. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  5. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  6. What solvents can be used to dissolve Azoxymethane?

    Azoxymethane is soluble in water, ether, ethanol, and chloroform. The reported solubility in chlorform is 200 mg/mL, and in water is 100 mg/mL.

  7. How should stock solutions of Azoxymethane be stored, and for how long can they be kept?

    No solution stability studies have been performed by Sigma-Aldrich. Because the solution stability is unknown, solutions should be prepared fresh for use.

  8. How does azoxymethane act to cause cancers?

    Azoxymethane is a methylating agent which forms 6-O-methylguanine in DNA.  Unless this methylated base is repaired by cellular enzymes, it results in a base mismatch that subsequently causes tumors in the tissue.

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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