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Merck
CN

A2987

Atractylenolide III

≥98% (HPLC)

别名:

8β-Hydroxyasterolide, Codonolactone

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关于此项目

经验公式(希尔记法):
C15H20O3
化学文摘社编号:
分子量:
248.32
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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biological source

Atractylodes macrocephala Koidz.

Quality Segment

assay

≥98% (HPLC)

form

powder or crystals

color

white to off-white

solubility

methanol: 1 mg/mL, clear, colorless

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

2-8°C

SMILES string

CC1=C2C[C@H]3C(=C)CCC[C@]3(C)C[C@]2(O)OC1=O

InChI

1S/C15H20O3/c1-9-5-4-6-14(3)8-15(17)12(7-11(9)14)10(2)13(16)18-15/h11,17H,1,4-8H2,2-3H3/t11-,14+,15-/m0/s1

InChI key

FBMORZZOJSDNRQ-GLQYFDAESA-N

General description

Atractylenolide III is a biologically active sesquiterpene compound, extracted from the roots of Atractylodes macrocephala Koidzumi.

Application

Atractylenolide III has been used to examine its effects on the energy metabolism in the skeletal muscles of mouse.
Atractylenolide III, a sesquiterpenoid, is a phytochemical that may be used to study its anti-inflammatory and anti-angiogenesis activities. Atractylenolide III may be used and studied as an inhibitor of aromatases and inducer of apoptosis. Atractylenolide III may be used to study its sonic hedgehog pathway dependent mechanism of action as an inducer of chondrogenic differentiation. Atractylenolide III may be used as a reference material in assays to detect its presence in plant root extracts and biological milieu such as plasma.

Biochem/physiol Actions

Atractylenolide III has been shown to possess anti-inflammatory effects and also offers gastroprotection. It also shows acaricidal properties and hence has the potential to be used as an agent for the control of dust mites. Atractylenolide III is capable of regulating the secretion and expression of Interleukin-6, thereby mediating the immune response caused by mast cells.
Atractylenolide III possesses anti-inflammatory and anticancer properties.


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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