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A3009

4-Androsten-11β-ol-3,17-dione

Name: 4-Androsten-11&#946;-ol-3,17-dione
Brand: SIGMA

≥98.00% (TLC), Androgen hormone, powder

别名:

11β-Hydroxy-4-androstene-3,17-dione

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关于此项目

经验公式（希尔记法）:

C₁₉H₂₆O₃

化学文摘社编号:

382-44-5

分子量:

302.41

UNSPSC Code:

51111800

PubChem Substance ID:

24890715

NACRES:

NA.77

MDL number:

MFCD00051131

Assay:

≥98.00% (TLC)

Form:

powder

Quality level:

200

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属性

产品名称

4-Androsten-11β-ol-3,17-dione,

assay

≥98.00% (TLC)

Quality Level

200

form

powder

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

solubility

chloroform: 49-51 mg/mL, clear, colorless to faintly yellow

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@]4(C)C(=O)CC[C@@]24[H]

InChI

1S/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-15,17,21H,3-8,10H2,1-2H3/t13-,14-,15-,17+,18-,19-/m0/s1

InChI key

WSCUHXPGYUMQEX-KCZNZURUSA-N

说明

Biochem/physiol Actions

11β-Hydroxy-4-androstene-3,17-dione is a naturally occurring steroid that is primarily, if not strictly, produced in adrenal tissue. In diseases such as Cushing′s syndrome, adrenal-originated hyperandrogenism, and congenital adrenal hyperplasia, plasma 11β levels are very high. Plasma 11β concentration is very low in congenital 11-hydroxylase deficiency and adrenal insufficiency.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000486100

0000486099

0000458179

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Effects of adrenocorticotropin on adrenal and plasma 11 beta-hydroxyandrostenedione in the guinea pig and determination of its relative androgen potency.

B Bélanger et al.

Steroids, 58(1), 29-34 (1993-01-01)

In order to gain a better understanding of adrenal steroid production in guinea pigs, adrenocorticotropin (ACTH) was administered to castrated adult guinea pigs and a series of C-21 and C-19 steroid levels were determined in both adrenals and plasma over

Sex steroids and the initiation of puberty in male African catfish (Clarias gariepinus).

J E Cavaco et al.

The American journal of physiology, 275(6 Pt 2), R1793-R1802 (1998-12-09)

The effects of sex steroids on spermatogenesis and testicular androgen secretion were studied in juvenile (spermatogonia present in testes) African catfish. Fish were implanted with Silastic pellets containing 11-ketotestosterone (KT), 11beta-hydroxyandrostenedione (OHA), androstenetrione (OA), androstenedione (A), testosterone (T), 5alpha-dihydrotestosterone (DHT)

Steroidogenesis in guinea pig adrenal cortex: effects of ACTH on steroid secretion and steroidogenic enzyme activities and expression.

P H Provencher et al.

The Journal of steroid biochemistry and molecular biology, 43(8), 855-862 (1992-12-01)

In this study, we investigated guinea pig adrenal steroidogenesis, specially, C19 steroid production. Analysis of adrenal steroids by high performance liquid chromatography and gas chromatography indicated the presence of androstenedione and 11β-hydroxyandrostenedione. Adrenal androstenedione and 11β-hydroxyandrostenedione levels were stimulated by

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A3009-100MG	04061832847436
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