A3010
酰基酶Ⅰ 来源于猪肾脏
Grade I, lyophilized powder, ≥1500 units/mg protein
别名:
N-酰基氨基酸酰胺水解酶, 氨基酰化酶
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-732-3
MDL number:
Specific activity:
≥1500 units/mg protein
type
Grade I
form
lyophilized powder
specific activity
≥1500 units/mg protein
composition
Protein, ≥60%
UniProt accession no.
storage temp.
−20°C
Quality Level
Gene Information
pig ... ACY1(396930)
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Application
猪肾中的酰化酶 I 已被用于研究各种 S-烷基-N-乙酰基-L-半胱氨酸及其碳、氧类似物的酰化酶 I 催化的脱乙酰作用 。酰化酶 I 可能有助于催化 N-乙酰氨基酸生成对映体纯的 L-氨基酸 。
Biochem/physiol Actions
酰化酶 I 催化 N-乙酰基-L-半胱氨酸和 S-烷基-N-乙酰基-L-半胱氨酸的脱乙酰化。正丁基丙二酸是酰化酶 Ⅰ 的抑制剂。S-烷基-N-乙酰基-L-半胱氨酸与短 (C0-C3) 和不分枝 S-烷基取代已被发现是良好的酰化酶 I 底物。
Analysis Note
缩二脲法测定蛋白
Other Notes
一个单元将在pH 7.0 和 25°C 条件下每小时水解 1.0μmol N-乙酰- L -蛋氨酸。
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
动植物源性产品
此项目有
Debby Ngo et al.
JCI insight, 6(5) (2021-02-17)
Recent advances in proteomic technologies have made high-throughput profiling of low-abundance proteins in large epidemiological cohorts increasingly feasible. We investigated whether aptamer-based proteomic profiling could identify biomarkers associated with future development of type 2 diabetes (T2DM) beyond known risk factors.
Y Fukagawa et al.
The Journal of antibiotics, 33(6), 543-549 (1980-06-01)
PS-5 was deacetylated to NS-5 (deacetylated PS-5) by l-amino acid acylase from porcine kidney and D-amino acid acylase from Streptomyces olivaceus but not by l-amino acid acylase from Aspergillus sp. Using PS-5, N-chloroacetyl-l-phenylalanine and N-chloroacetyl-D-valine as substrates, acylase producers were
Jinit Masania et al.
Oxidative medicine and cellular longevity, 2019, 4851323-4851323 (2019-12-13)
Glycation, oxidation, nitration, and crosslinking of proteins are implicated in the pathogenic mechanisms of type 2 diabetes, cardiovascular disease, and chronic kidney disease. Related modified amino acids formed by proteolysis are excreted in urine. We quantified urinary levels of these
K Kubo et al.
The Journal of antibiotics, 33(6), 556-565 (1980-06-01)
L-Amino acid acylase and D-amino acid acylase were stable below 50 degrees C, although the D-enzyme was more thermostable than the L-enzyme at higher temperatures. At 30 degrees C they showed the highest reaction velocity in phosphate buffer of pH
Safiye Selen Özcan et al.
Journal of industrial microbiology & biotechnology, 46(8), 1103-1111 (2019-04-26)
Microbial contamination in metalworking systems is a critical problem. This study determined the microbial communities in metalworking fluids (MWFs) from two machining shops and investigated the effect of quorum sensing inhibition (QSI) on biofilm growth. In both operations, biofilm-associated and
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