A3737
Cefepime hydrochloride
别名:
Cefepime dihydrochloride monohydrate
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关于此项目
线性分子式:
C19H25N6O5S2Cl · HCl · H2O
化学文摘社编号:
分子量:
571.50
MDL number:
UNSPSC Code:
51282610
NACRES:
NA.85
form
powder
Quality Segment
color
white to faint yellow
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
mode of action
cell wall synthesis | interferes
storage temp.
−20°C
SMILES string
[s]1c(nc(c1)\C(=N\OC)\C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)C[N+]4(CCCC4)C)N.[Cl-].[Cl-].O.[H+]
InChI
1S/C19H24N6O5S2.2ClH.H2O/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11;;;/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29);2*1H;1H2/b23-12-;;;/t13-,17-;;;/m1.../s1
InChI key
LRAJHPGSGBRUJN-OMIVUECESA-N
General description
Cefepime is a semi-synthetic fourth-generation cephalosporin. It is resistant to hydrolysis by common plasmid and/or chromosomally-mediated β-lactamases.
Application
Cefepime was used in antimicrobial susceptibility testing for Acinetobacter baumannii and extended-spectrum-β-lactamase-producing Escherichia coli isolated from various samples.
Biochem/physiol Actions
Cefepime is a broad-spectrum cephalosporin with activity against Gram-positive and Gram-negative bacteria. It binds to penicillin-binding proteins and disrupts the cell wall synthesis.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable