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A3737

Cefepime hydrochloride

Name: Cefepime hydrochloride
Brand: SIGMA

别名:

Cefepime dihydrochloride monohydrate

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关于此项目

线性分子式:

C₁₉H₂₅N₆O₅S₂Cl · HCl · H₂O

化学文摘社编号:

123171-59-5

分子量:

571.50

MDL number:

MFCD01687679

UNSPSC Code:

51282610

NACRES:

NA.85

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属性

form

powder

Quality Segment

200

color

white to faint yellow

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

cell wall synthesis | interferes

storage temp.

−20°C

SMILES string

[s]1c(nc(c1)\C(=N\OC)\C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)O)C[N+]4(CCCC4)C)N.[Cl-].[Cl-].O.[H+]

InChI

1S/C19H24N6O5S2.2ClH.H2O/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11;;;/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29);2*1H;1H2/b23-12-;;;/t13-,17-;;;/m1.../s1

InChI key

LRAJHPGSGBRUJN-OMIVUECESA-N

说明

General description

Cefepime is a semi-synthetic fourth-generation cephalosporin. It is resistant to hydrolysis by common plasmid and/or chromosomally-mediated β-lactamases.

Application

Cefepime was used in antimicrobial susceptibility testing for Acinetobacter baumannii and extended-spectrum-β-lactamase-producing Escherichia coli isolated from various samples.

Biochem/physiol Actions

Cefepime is a broad-spectrum cephalosporin with activity against Gram-positive and Gram-negative bacteria. It binds to penicillin-binding proteins and disrupts the cell wall synthesis.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c