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Merck
CN

A3940

Sigma-Aldrich

1-氨基苯并三唑

greener alternative

≥98% (TLC), powder, cytochrome P450 inhibitor

别名:

1-苯并三唑胺, ABT

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关于此项目

经验公式（希尔记法）:
C6H6N4
CAS Number:
1614-12-6
分子量:
134.14
Beilstein:
607843
MDL编号:
MFCD00132902
UNSPSC代码:
12352200
PubChem化学物质编号:
24278226
NACRES:
NA.77

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Product Name

1-氨基苯并三唑,

方案

≥98% (TLC)

质量水平

200

表单

powder

环保替代产品得分

old score: 93
new score: 46
Find out more about DOZN™ Scoring

环保替代产品特性

Waste Prevention
Safer Solvents and Auxiliaries
Inherently Safer Chemistry for Accident Prevention
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

81-84 °C (lit.)

溶解性

ethanol: 49-51 mg/mL, clear, pale yellow to yellow

环保替代产品分类

, Re-engineered

SMILES字符串

Nn1nnc2ccccc12

InChI

1S/C6H6N4/c7-10-6-4-2-1-3-5(6)8-9-10/h1-4H,7H2

InChI key

JCXKHYLLVKZPKE-UHFFFAOYSA-N

基因信息

human ... CYP1A2(1544)

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相关类别

一般描述

我们竭诚为您带来满足绿色替代产品四大类别要求的替代产品。本品属于重新设计产品类别，在绿色化学原理、“废物预防”、“溶剂和助剂安全性”以及“事故预防化学本安性”方面取得了关键改进。点击此处查看其 DOZN 记分卡。

应用

使用1-氨基苯并三唑作为细胞色素P450酶抑制剂，研究雌性激素对H2O2诱导的老年大鼠血管平滑肌细胞早衰的影响此外，它还被用于研究17β-雌二醇雌激素受体介导的效应。

生化/生理作用

1-氨基苯并三唑(1-ABT)在药物研究中用作体外工具。它能区分P450和非P450酶系统。1-ABT通过P450酶中血红素辅基的共价改变表现出抑制作用。
细胞色素 P450 和氯过氧化物酶的自杀抑制剂。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000420467
0000420467
0000410697
0000410697
0000401293

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