Anti-α_1B Adrenergic Receptor antibody produced in rabbit

Adrenergic receptors (ARs) belong to the G protein-coupled receptor superfamily that interacts with epinephrine and norepinephrine. There are nine receptor subtypes which include three α1AR subtypes (α_1A/D, α_1B, and α_1C), three α2ARs (α_2A, α_2B, and α_2C), and three βAR subtypes (β1, β2, and β3). Adrenergic receptors have been implicated in many diseases such as hypertension, glaucoma, cardiac disorders, diabetes, impotence and depression. Rabbit Anti-α_1B Adrenergic Receptor antibody specifically recognizes human α_1B adrenergic receptor.

synthetic peptide corresponding to the C-terminal domain of human α_1B adrenergic receptor. The immunizing peptide has 85% homology with the rat gene and 90% homology with the mouse gene.

Anti-α_1B Adrenergic Receptor antibody can be used for immunohistochemistry at 3μg/ml using artery, tunica intima and tunica media tissues.

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

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