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线性分子式:
C8H6N3O2Na
化学文摘社编号:
分子量:
199.14
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83
MDL number:
产品名称
鲁米诺 钠盐,
SMILES string
O=C1NN([Na])C(C2=CC=CC(N)=C21)=O
InChI
1S/C8H7N3O2.Na/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12;/h1-3H,(H4,9,10,11,12,13);/q;+1/p-1
InChI key
RVJVDCVIJCBUTH-UHFFFAOYSA-M
assay
≥98% (titration)
form
powder and chunks
solubility
water: 50 mg/mL, clear to very slightly hazy, colorless to faint red
Quality Level
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Application
鲁米诺钠盐已用于:
- 作为生物发光测定实验的MEBSS 缓冲液组分,检测全血样品中的过氧化物酶活性
- 免疫沉淀分析全细胞裂解物中的蛋白质相互作用
- CD45+ 和CD45−细胞中的体外活性氧 (ROS) 定量
Biochem/physiol Actions
鲁米诺(Luminol)是一种对氧化还原敏感的化学发光化合物。含有氧原子的鲁米诺碱性水溶液接触铁氰化钾等氧化剂时,会发出蓝光。这种成分具有很高的稳定性,适用于分析化学、冶金、生物化学、法医学等各个领域的活性物质检测。鲁米诺有望检测氧化代谢缺陷(如慢性肉芽肿病和髓过氧化物酶缺乏症)期间的离体中性粒细胞缺陷。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
New Developments in Chemiluminescence Research
Gill, Steven, K.
Aldrichimica Acta, 16, 59-59 (1983)
Chemiluminescence detection in analytical chemistry
Lancaster, J. Steven
Endeavour, 16, 194-194 (1992)
Yantu Zhang et al.
Journal of chromatography. A, 1154(1-2), 260-268 (2007-04-24)
A novel method was developed for the simultaneous determination of glucocorticoid residues such as triamcinolone (TR), prednisolone (PR), hydrocortisone (HC), cortisone (CO), methylprednisolone (MP), dexamethasone (DE) and triamcinolone acetonide (TA) by high-performance liquid chromatography (HPLC) coupled with chemiluminescence (CL) detection.
Luminol Chemiluminescence-Delay Method for Determination of Copper(II)
Kamidate, Tamio; Ishikawa, Atsushi; Watanabe, Hiroto.
Bulletin of the Chemical Society of Japan, 65, 1591-1591 (1992)
Chemilunimescence of luminol: The chemcial reaction
White E H, et al.
ACS Chemical Biology, 86(5), 940-941 (1964)
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