A5043
腺苷脱氨酶 来源于牛脾脏
Type X, buffered aqueous glycerol solution, ≥130 units/mg protein
别名:
腺苷脱氨基酶
生物来源
bovine spleen
质量水平
类型
Type X
表单
buffered aqueous glycerol solution
比活
≥130 units/mg protein
分子量
32.5-33 kDa
痕量阳离子
NH4+: ≤10 μg/mg protein
UniProt登记号
异质活性
alkaline phosphatase ≤0.01%
guanase ≤0.01%
nucleoside phosphorylase ≤0.1%
储存温度
2-8°C
基因信息
cow ... ADA(280712)
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一般描述
分子量：32.5-33 kDa
pI: 4.85
pI: 4.85
应用
来自牛脾脏的腺苷脱氨酶已被用于biostrip的固定化，用于稳定性和催化研究。
腺苷脱氨酶可用于各种分子生物学测定，如甘油释放测定。 腺苷脱氨酶是治疗联合免疫缺陷病的潜在靶标。
生化/生理作用
腺苷脱氨酶是一种嘌呤分解代谢酶，其催化腺苷和2′-脱氧腺苷的脱氨基作用，它们具有几乎相同的特异性。它广泛存在于哺乳动物组织中，腺苷脱氨酶缺乏与严重的联合免疫缺陷病有关。
外形
溶于50%甘油，5 mM磷酸钾，pH 6.0
分析说明
通过缩二脲法测定的蛋白质。
其他说明
一个酶活性单位是指在pH 7.5、25℃条件下，每分钟将1.0 μmole 腺苷脱氨基形成肌苷所需的酶量。
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
低风险生物材料
动植物源性产品
此项目有
Adenosine reagent-free detection by co-immobilization of adenosine deaminase and phenol red on an optical biostrip
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Nucleic acids research, 41(4), 2581-2593 (2013-01-01)
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Neutropenia and myeloid dysplasia in a patient with delayed-onset adenosine deaminase deficiency.
Keiko Nomura et al.
Pediatric blood & cancer, 60(5), 885-886 (2013-01-22)
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