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Merck
CN

A5043

腺苷脱氨酶 来源于牛脾脏

Type X, buffered aqueous glycerol solution, ≥130 units/mg protein

别名:

腺苷脱氨基酶

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化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
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产品名称

腺苷脱氨酶 来源于牛脾脏, Type X, buffered aqueous glycerol solution, ≥130 units/mg protein

biological source

bovine spleen

type

Type X

form

buffered aqueous glycerol solution

specific activity

≥130 units/mg protein

mol wt

32.5-33 kDa

cation traces

NH4+: ≤10 μg/mg protein

UniProt accession no.

foreign activity

alkaline phosphatase ≤0.01%
guanase ≤0.01%
nucleoside phosphorylase ≤0.1%

storage temp.

2-8°C

Quality Level

Gene Information

cow ... ADA(280712)

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Analysis Note

通过缩二脲法测定的蛋白质。

Application

来自牛脾脏的腺苷脱氨酶已被用于biostrip的固定化,用于稳定性和催化研究。
腺苷脱氨酶可用于各种分子生物学测定,如甘油释放测定。 腺苷脱氨酶是治疗联合免疫缺陷病的潜在靶标。

Biochem/physiol Actions

腺苷脱氨酶是一种嘌呤分解代谢酶,其催化腺苷和2′-脱氧腺苷的脱氨基作用,它们具有几乎相同的特异性。它广泛存在于哺乳动物组织中,腺苷脱氨酶缺乏与严重的联合免疫缺陷病有关。

General description

分子量:32.5-33 kDa

pI: 4.85

Other Notes

一个酶活性单位是指在pH 7.5、25℃条件下,每分钟将1.0 μmole 腺苷脱氨基形成肌苷所需的酶量。

Physical form

溶于50%甘油,5 mM磷酸钾,pH 6.0

存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

低风险生物材料
动植物源性产品
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Lot/Batch Number

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Adenosine reagent-free detection by co-immobilization of adenosine deaminase and phenol red on an optical biostrip
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Diabetes, 59(1), 17-25 (2009-10-17)
White adipose tissue (WAT) and brown adipose tissue (BAT) play distinct roles in adaptation to changes in nutrient availability, with WAT serving as an energy store and BAT regulating thermogenesis. We previously showed that mice maintained on a leucine-deficient diet
Leila Antonangelo et al.
Clinics (Sao Paulo, Brazil), 67(11), 1259-1263 (2012-11-28)
Pleural tuberculosis is the most frequently occurring form of extra pulmonary disease in adults. In up to 40% of cases, the lung parenchyma is concomitantly involved, which can have an epidemiological impact. This study aims to evaluate the pleural and
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Environmental toxicology and pharmacology, 35(1), 1-12 (2012-12-12)
Immune status of waste management workers (WMW) with underlying systemic inflammation was assessed to identify useful immune-related biomarkers of occupational health and safety. Clinical history of WMW revealed high prevalence of respiratory symptoms alongside gastrointestinal and musculoskeletal complaints relative to
George R Thompson et al.
Chest, 143(3), 776-781 (2012-11-29)
In a patient with positive serum serology for coccidioidomycosis, the differential diagnosis of concurrent pleural effusions can be challenging. We, therefore, sought to clarify the performance characteristics of biochemical, serologic, and nucleic-acid-based testing in an attempt to avoid invasive procedures.

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