应用
D-氨基酸氧化酶（DAO）是治疗慢性疼痛和精神分裂症的潜在靶分子。 D-氨基酸氧化酶可用于将D-氨基酸氧化成其相应的亚氨基酸。
其他说明
在过氧化氢酶存在下，一单位酶在pH 8.3、25℃条件下每分钟可使1.0 μmM D-丙氨酸氧化脱氨成丙酮酸。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
低风险生物材料
此项目有
Jin-Lu Huang et al.
Amino acids, 43(5), 1905-1918 (2012-09-22)
D-Amino acid oxidase (DAAO), a FAD-dependent peroxisomal flavoenzyme that catalyzes oxidation of D-amino acids to hydrogen peroxide, is distributed in the spinal cord almost exclusively expressed within astrocytes. The present study aims to explore potential contributions of spinal DAAO to
Norihiro Shibuya et al.
Nature communications, 4, 1366-1366 (2013-01-24)
In eukaryotes, hydrogen sulphide acts as a signalling molecule and cytoprotectant. Hydrogen sulphide is known to be produced from L-cysteine by cystathionine β-synthase, cystathionine γ-lyase and 3-mercaptopyruvate sulfurtransferase coupled with cysteine aminotransferase. Here we report an additional biosynthetic pathway for
Natsuki Matsumoto et al.
Methods in molecular biology (Clifton, N.J.), 1887, 23-31 (2018-12-07)
Fermented foods produced using edible microorganisms have been consumed worldwide since ancient times. Microorganisms produce some healthy functional substances. Recently, many people have been attracted to the notion that D-body amino acids have healthy functional effects. D-body amino acids convert
R M Abou El-Magd et al.
Journal of psychopharmacology (Oxford, England), 24(7), 1055-1067 (2009-03-31)
D-Amino acid oxidase (DAO) has been established to be involved in the oxidation of D-serine, an allosteric activator of the N-methyl-D-aspartate-type glutamate receptor in the brain, and to be associated with the onset of schizophrenia. The effect of risperidone, a
Cindy J Lee et al.
Metabolites, 12(9) (2022-09-24)
The pancreatic islets of Langerhans are clusters of cells that function as endocrine units synthesizing and releasing insulin and a range of additional peptide hormones. The structural and chemical characteristics of islets change during type 2 diabetes development. Although a
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