Ang-1 is a ligand with affinity to the Tie-2 receptor tyrosine kinase, which is expressed in early hematopoietic and endothelial cells. Both Ang-1 and Tie-2 play critical roles in embryonic angiogenesis as well as adult vascular integrity.

Ligand with affinity to the Tie-2 receptor tyrosine kinase. Both Ang-1 and Tie-2 play critical roles in embryonic angiogenesis as well as adult vascular integrity.

Lyophilized from a 0.2 μm filtered solution in 50 mM Tris and 0.5 M sodium chloride, pH 6.5, containing 50 μg bovine serum albumin per 1 μg of cytokine.

The biological activity is measured by its ability to inhibit serum deprivation induced apoptosis in HUVE cells.