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A5486

偶氮甲烷

13.4 M, ≥98%

别名:

AOM

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关于此项目

线性分子式:
CH3N=N(→O)CH3
化学文摘社编号:
25843-45-2
分子量:
74.08
NACRES:
NA.25
PubChem Substance ID:
329770827
UNSPSC Code:
12352124
MDL number:
MFCD00126912
Assay:
≥98%
Form:
liquid
Quality level:
200
Storage condition:
(Keep container tightly closed in a dry and well-ventilated place.)
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Quality Level

200

assay

≥98%

form

liquid

composition

methylene chloride, ≤1%

storage condition

(Keep container tightly closed in a dry and well-ventilated place.)

concentration

13.4 M

color

colorless

bp

97-99 °C (lit.)

density

0.991 g/mL at 25 °C (lit.)

application(s)

genomic analysis

storage temp.

−20°C

SMILES string

C\N=[N+](/C)[O-]

InChI

1S/C2H6N2O/c1-3-4(2)5/h1-2H3/b4-3+

InChI key

DGAKHGXRMXWHBX-ONEGZZNKSA-N

General description

偶氮甲烷（AOM）是一种功能强大的实验室化学品，用于研究癌症，特别是结肠癌的发生、进展和预防。它可用作引发肿瘤形成的致癌物和导致DNA特异性改变的基因突变剂。

Application

氧化偶氮甲烷（AOM），一种基因突变剂，可与硫酸葡聚糖钠（DSS）一起用于在实验室动物中创建癌症模型，从而用于研究癌症进展和化学预防的机制。

Biochem/physiol Actions

诱导DNA中O6-甲基鸟嘌呤加合物的致癌物导致G→A转变。 在实验动物的结肠中诱导肿瘤生成，并用于研究癌症进展和化学预防的机制。

Features and Benefits

用途广泛，适用于各种实验室和研究应用。

Other Notes

为避免实验动物过早死亡，在实验设计中确定合适的氧化偶氮甲烷剂量至关重要。
如需了解生化试剂系列的更多信息，请填写此表。

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

存储类别

3 - Flammable liquids

wgk

WGK 3

flash_point_f

75.2 °F

flash_point_c

24 °C

法规信息

危险化学品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000515941
0000515941
0000503884
0000503882
0000503884

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全球贸易项目编号

货号GTIN
A5486-100MG04061837839597
A5486-25MG04061837839603

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