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A5585

5-（N-甲基-N-异丁基）阿米洛利

≥98% (TLC), powder

别名:

MIA

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关于此项目

经验公式（希尔记法）:
C11H18ClN7O
化学文摘社编号:
96861-65-3
分子量:
299.76
NACRES:
NA.77
PubChem Substance ID:
24278228
UNSPSC Code:
12352200
MDL number:
MFCD00078567
Assay:
≥98% (TLC)
Form:
powder
Quality level:
200
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Quality Level

200

assay

≥98% (TLC)

form

powder

mp

200-201 °C

solubility

methanol: 9.80-10.20 mg/mL, clear, pale yellow to yellow

storage temp.

2-8°C

SMILES string

CC(C)CN(C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N

InChI

1S/C11H18ClN7O/c1-5(2)4-19(3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20)

InChI key

RVIUMPLAOXSSGN-UHFFFAOYSA-N

Gene Information

human ... SCNN1A(6337), SCNN1B(6338), SCNN1D(6339), SCNN1G(6340)
mouse ... Scnn1a(20276), Scnn1b(20277), Scnn1d(140501), Scnn1g(20278)
rat ... Scnn1a(25122), Scnn1b(24767), Scnn1g(24768)

Application

5-（N-甲基-N-异丁基）阿米洛利是Na+/H+反向转运的有效阻滞剂。 5-（N-甲基-N-异丁基）阿米洛利已用于研究对酸中毒的早期细胞反应。

Biochem/physiol Actions

Na+/H+反向转运的有效阻滞剂。 可能的抗肿瘤药物。

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000115952
0000113689
0000091870
13150404
118M4067V

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