A5880
D-苯丙胺 半硫酸盐
别名:
(+)-α-甲基苯乙胺 半硫酸盐, 右旋苯丙胺 半硫酸盐
表单
powder
质量水平
药品控制
USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
溶解性
H2O: soluble
ethanol: soluble
应用
forensics and toxicology
SMILES字符串
OS(O)(=O)=O.CC(N)Cc1ccccc1.CC(N)Cc2ccccc2
InChI
1S/2C9H13N.H2O4S/c2*1-8(10)7-9-5-3-2-4-6-9;1-5(2,3)4/h2*2-6,8H,7,10H2,1H3;(H2,1,2,3,4)/t2*8-;/m00./s1
InChI key
PYHRZPFZZDCOPH-QXGOIDDHSA-N
基因信息
human ... SLC18A2(6571)
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应用
D-苯丙胺半硫酸盐已用于氧化发酵 (OF) 测试和探索性测试。
生化/生理作用
D-苯丙胺是苯丙胺的活性异构体。它通过将单胺从其囊泡储存位点置换出来,诱导儿茶酚胺和血清素的释放,阻断儿茶酚胺再摄取。
法规信息
监管及禁止进口产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Timothy J O'Neal et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 45(8), 1251-1262 (2019-11-21)
Opioid addiction has been declared a public health emergency, with fatal overdoses following relapse reaching epidemic proportions and disease-associated costs continuing to escalate. Relapse is often triggered by re-exposure to drug-associated cues, and though the neural substrates responsible for relapse
A M Barr et al.
Pharmacology, biochemistry, and behavior, 64(3), 597-604 (1999-11-05)
The present study sought to determine the effect of withdrawal from an escalating dose schedule of d-amphetamine on sexual behavior in male rats. Tests were conducted every 5 days until stable levels of sexual behavior were obtained. With repeated testing
Cedric Jackson et al.
Behavioural brain research, 361, 131-138 (2018-12-15)
Although scientific research using mammalian models has made great strides in uncovering the enigmatic neural and molecular mechanisms orchestrating the state of drug addiction, a complete understanding has thus far eluded researchers. The complexity of the task has led to
J Cartmell et al.
The Journal of pharmacology and experimental therapeutics, 291(1), 161-170 (1999-09-22)
Previous animal studies have indicated that drugs targeted at metabotropic glutamate (mGlu) receptors may be useful for treatment of psychosis. In this article, the effects of the novel, potent, and selective mGlu2/3 receptor agonists LY354740 and LY379268, and the clinically
Nina Mansouri-Guilani et al.
Journal of neurochemistry, 148(6), 779-795 (2018-12-18)
Several subtypes of modulatory neurons co-express vesicular glutamate transporters (VGLUTs) in addition to their cognate vesicular transporters. These neurons are believed to establish new forms of neuronal communication. The atypical VGLUT3 is of particular interest since in the striatum this
Chromatograms
suitable for GC
application for HPLC
suitable for GC
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