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关于此项目
经验公式(希尔记法):
C5H15N2O3PS · 3 H2O
化学文摘社编号:
分子量:
268.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Quality Level
assay
≥97% (TLC)
form
powder
storage temp.
2-8°C
SMILES string
OP(SCCNCCCN)(O)=O.O.O.O
InChI
1S/C5H15N2O3PS.3H2O/c6-2-1-3-7-4-5-12-11(8,9)10;;;/h7H,1-6H2,(H2,8,9,10);3*1H2
InChI key
TXQPXJKRNHJWAX-UHFFFAOYSA-N
Application
氨磷汀可以使用生长抑素类似物减轻辐射损伤并减少吸收的肾脏辐射剂量,从而在PRRT期间提供肾脏保护。氨磷汀可补救辐射对鼠下颌骨矿化能力的退化作用。
Biochem/physiol Actions
辐射防护剂。选择性地保护正常组织免受抗肿瘤放射疗法的破坏作用。选择性归因于正常组织的优先摄取以及随后对2-(3-氨基丙基)氨基乙硫醇的代谢活化。
Hazard Classifications
Acute Tox. 4 Oral
signalword
Warning
hcodes
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Marleen Melis et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 53(5), 749-753 (2012-04-13)
Megalin-mediated renal retention of radiolabeled somatostatin analogs may lead to nephrotoxicity during peptide receptor radionuclide therapy (PRRT). The cytoprotective agent amifostine protected rats from long-term nephrotoxicity after PRRT with (177)Lu-DOTA,Tyr(3)-octreotate. This study describes the direct effect of amifostine on kidney
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A5922-100MG | 04061833376607 |
