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Merck
CN

A6237

Sigma-Aldrich

马铃薯来源腺苷三磷酸双磷酶

recombinant, expressed in Pichia pastoris, ATPase ≥1000 units/mg protein, lyophilized powder

别名:

三磷酸腺苷双磷酸酶 来源于马铃薯, 腺苷 5′-三磷酸酶, 腺苷 5′-二磷酸酶

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关于此项目

MDL编号:
UNSPSC代码:
12352204
NACRES:
NA.54
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重组

expressed in Pichia pastoris

质量水平

表单

lyophilized powder

ATPase activity

≥1000 units/mg protein

运输

wet ice

储存温度

−20°C

相关类别

一般描述

腺苷三磷酸双磷酶又称 ATP-二磷酸水解酶,在各种动植物组织中都有表达。商业化的腺苷三磷酸双磷酸酶分离自马铃薯块茎。

生化/生理作用

在存在二价阳离子的情况下,磷酸酯酶可水解三磷酸和二磷酸核苷的磷酸酐键。它对核苷酸具有广泛的底物特异性。这种酶的这一特性使其适于许多不同的生物技术应用,包括 DNA 测序和血小板聚集抑制。

象形图

Health hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Resp. Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Subin Mao et al.
Lab on a chip, 21(16), 3128-3136 (2021-06-29)
Integrins are key players in platelet adhesion and aggregation. Integrin molecular tensions, the forces transmitted by integrin molecules, are regulated by both mechanical and biochemical cues, and the outside-in and inside-out signaling has been extensively studied. While the mechanical properties
Cloning, sequencing, and expression of a human brain ecto-apyrase related to both the ecto-ATPases and CD39 ecto-apyrases1.
Smith T M & Kirley T L
Biochimica et Biophysica Acta, 1386(1), 65-78 (1998)
Methylotrophic yeast Pichia pastoris as a host for production of ATP-diphosphohydrolase (apyrase) from potato tubers (Solanum tuberosum).
Nourizad N, et al.
Protein Expression and Purification, 27(2), 229-237 (2003)
Xuan Zhang et al.
European journal of medicinal chemistry, 199, 112397-112397 (2020-05-11)
Targeting BCL-XL via PROTACs is a promising strategy in reducing BCL-XL inhibition associated platelet toxicity. Recently, we reported potent BCL-XL PROTAC degraders that recruit VHL or CRBN E3 ligase. However, low protein expression or mutation of the responsible E3 ligase
Minfei Su et al.
Molecular cell, 80(1), 59-71 (2020-08-21)
Cardiac disease remains the leading cause of morbidity and mortality worldwide. The β1-adrenergic receptor (β1-AR) is a major regulator of cardiac functions and is downregulated in the majority of heart failure cases. A key physiological process is the activation of

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