Quality Level
assay
≥99%
form
powder
mp
140-143 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
SMILES string
[Br-].CC(=O)OCC[N+](C)(C)C
InChI
1S/C7H16NO2.BrH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
InChI key
ZEHGKSPCAMLJDC-UHFFFAOYSA-M
Gene Information
human ... CHRM3(1131)
Application
乙酰胆碱是胆碱能突触的内源性神经递质,可放大肌膜的动作电位,从而诱导肌肉收缩。溴化乙酰胆碱可用作乙酰胆碱受体激动剂,以鉴定、表征和区分胆碱能受体的类型。溴化乙酰胆碱可用作抑制剂,以鉴定和表征天然和突变的丁酰胆碱酯酶。
Biochem/physiol Actions
胆碱能突触中的内源性神经递质,通过增强肌膜动作电位来触发肌肉收缩反应。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Scott A Hollingsworth et al.
Nature communications, 10(1), 3289-3289 (2019-07-25)
Allosteric modulators are highly desirable as drugs, particularly for G-protein-coupled receptor (GPCR) targets, because allosteric drugs can achieve selectivity between closely related receptors. The mechanisms by which allosteric modulators achieve selectivity remain elusive, however, particularly given recent structures that reveal
Endothelium-independent vasorelaxant effect of 20(S)-protopanaxadiol on isolated rat thoracic aorta.
Lu Gan et al.
Acta pharmacologica Sinica, 37(12), 1555-1562 (2016-09-13)
Ginsenosides are considered to be the major pharmacologically active ginseng constituents, whereas 20(S)-protopanaxadiol [20(S)-PPD] is the active metabolite of ginsenosides in gut. In this study we investigated the effect of 20(S)-PPD on isolated rat thoracic aortas as well as its
Carmela Nacci et al.
Vascular pharmacology, 87, 83-91 (2016-08-28)
Increased TNFα-mediated JNK signaling in the perivascular adipose tissue (PVAT) may contribute to the pathogenesis of vascular complications in T1DM by reducing adiponectin (Ad) synthesis and therefore impairing Ad-mediated activity in the contiguous blood vessel system. We evaluated whether in
Fábio H Silva et al.
PloS one, 11(12), e0166291-e0166291 (2016-12-10)
Sickle cell disease patients display priapism that may progress to erectile dysfunction. However, little is known about the pathophysiological alterations of corpus cavernosum in sickle cell disease. Thus, this study aimed to evaluate the functional and molecular alterations of sympathetic
Li-Yan Zhao et al.
Acta pharmacologica Sinica, 39(5), 875-884 (2018-03-30)
Xyloketal B (Xyl-B) is a novel marine compound isolated from mangrove fungus Xylaria sp. (No 2508). We previously showed that Xyl-B promoted endothelial NO release and protected against atherosclerosis through the Akt/eNOS pathway. Vascular NO production regulates vasoconstriction in central
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A6500-100G | 04061835515738 |
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