登录 查看组织和合同定价。
选择尺寸
关于此项目
线性分子式:
(CH3)3N(Br)CH2CH2OCOCH3
化学文摘社编号:
分子量:
226.11
UNSPSC Code:
51151519
NACRES:
NA.25
PubChem Substance ID:
EC Number:
200-622-4
Beilstein/REAXYS Number:
3572117
MDL number:
产品名称
溴化乙酰胆碱(拟胆碱药), ≥99%
form
powder
InChI key
ZEHGKSPCAMLJDC-UHFFFAOYSA-M
InChI
1S/C7H16NO2.BrH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
SMILES string
[Br-].CC(=O)OCC[N+](C)(C)C
assay
≥99%
mp
140-143 °C (lit.)
solubility
water: 50 mg/mL, clear, colorless to faintly yellow
storage temp.
−20°C
Quality Level
Gene Information
human ... CHRM3(1131)
正在寻找类似产品? 访问 产品对比指南
Application
乙酰胆碱是胆碱能突触的内源性神经递质,可放大肌膜的动作电位,从而诱导肌肉收缩。溴化乙酰胆碱可用作乙酰胆碱受体激动剂,以鉴定、表征和区分胆碱能受体的类型。溴化乙酰胆碱可用作抑制剂,以鉴定和表征天然和突变的丁酰胆碱酯酶。
Biochem/physiol Actions
胆碱能突触中的内源性神经递质,通过增强肌膜动作电位来触发肌肉收缩反应。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Fábio H Silva et al.
PloS one, 11(12), e0166291-e0166291 (2016-12-10)
Sickle cell disease patients display priapism that may progress to erectile dysfunction. However, little is known about the pathophysiological alterations of corpus cavernosum in sickle cell disease. Thus, this study aimed to evaluate the functional and molecular alterations of sympathetic
Scott A Hollingsworth et al.
Nature communications, 10(1), 3289-3289 (2019-07-25)
Allosteric modulators are highly desirable as drugs, particularly for G-protein-coupled receptor (GPCR) targets, because allosteric drugs can achieve selectivity between closely related receptors. The mechanisms by which allosteric modulators achieve selectivity remain elusive, however, particularly given recent structures that reveal
Rahini Kakumanu et al.
Toxins, 11(4) (2019-04-04)
Russell's viper (Daboia russelii) venom causes a range of clinical effects in humans. Hypotension is an uncommon but severe complication of Russell's viper envenoming. The mechanism(s) responsible for this effect are unclear. In this study, we examined the cardiovascular effects
James A Angus et al.
European journal of pharmacology, 804, 111-116 (2017-03-17)
Endothelin receptor antagonists are approved for pulmonary arterial hypertension. Development of selective ET Human isolated pulmonary (i.d. 5.5mm) and human radial (i.d. 3.23mm) artery ring segments were mounted in organ baths for isometric force measurement. Single concentration-contraction curves to endothelin-1
Li-Yan Zhao et al.
Acta pharmacologica Sinica, 39(5), 875-884 (2018-03-30)
Xyloketal B (Xyl-B) is a novel marine compound isolated from mangrove fungus Xylaria sp. (No 2508). We previously showed that Xyl-B promoted endothelial NO release and protected against atherosclerosis through the Akt/eNOS pathway. Vascular NO production regulates vasoconstriction in central
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持