A6563
6-Anilinoquinoline-5,8-quinone
≥95% (TLC), solid
别名:
6-(Phenylamino)-5,8-quinolinedione, LY-83,583, LY83583
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C15H10N2O2
化学文摘社编号:
分子量:
250.25
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
产品名称
6-Anilinoquinoline-5,8-quinone, ≥95% (TLC), solid
InChI
1S/C15H10N2O2/c18-13-9-12(17-10-5-2-1-3-6-10)15(19)11-7-4-8-16-14(11)13/h1-9,17H
SMILES string
O=C1C=C(Nc2ccccc2)C(=O)c3cccnc13
InChI key
GXIJYWUWLNHKNW-UHFFFAOYSA-N
assay
≥95% (TLC)
form
solid
color
violet
solubility
0.1 M HCl: 1 mg/mL
methanol: 11 mg/mL
ethanol: 8 mg/mL
storage temp.
2-8°C
Quality Level
Application
6-Anilinoquinoline-5,8-quinone inhibits soluble guanylate cyclase and cGMP production. 6-Anilinoquinoline-5,8-quinone also blocks the release of intracellular Ca2+ and antigen-induced leukotrienes.
Biochem/physiol Actions
Blocks cGMP production; inhibits intracellular Ca2+ release; blocks the effects of nitric oxide. Inhibits antigen-induced leukotriene release.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Yao Teng et al.
Journal of plant physiology, 167(11), 885-889 (2010-02-23)
Cyclic guanosine 3',5'-monophosphate (cGMP) is an important second messenger in animals, and is emerging as a player in regulatory functions in plants. In this study, we investigated the role of cGMP in seed germination in Arabidopsis thaliana (Col-0). We demonstrated
Márcia Regina Ribeiro et al.
The Biological bulletin, 216(2), 138-148 (2009-04-16)
The cell signaling cascades that mediate pigment movements in crustacean chromatophores are not yet well established, although Ca(2+) and cyclic nucleotide second messengers are involved. Here, we examine the participation of cyclic guanosine monophosphate (cGMP) in pigment aggregation triggered by
Ole De Backer et al.
European journal of pharmacology, 590(1-3), 369-376 (2008-07-08)
This study investigated the possible interaction between the heme oxygenase (HO)/biliverdin reductase (BVR) and nitric oxide synthase (NOS) pathway in murine gastric fundus and jejunum, since previous studies have shown that both HO-2 and BVR are expressed in interstitial cells
R Hernanz et al.
Methods and findings in experimental and clinical pharmacology, 21(4), 243-251 (1999-07-10)
Bradykinin (BK) induced endothelium- and concentration-dependent relaxations in segments of porcine posterior descending coronary arteries submaximally precontracted with the thromboxane A2 mimetic, U-46619. The effects of BK were reduced by L-NG-monomethylarginine (L-NMMA) and 6-anilinoquinoline-5,8-quinone (LY-83583), respective inhibitors of nitric oxide
I Fleming et al.
British journal of pharmacology, 103(1), 1047-1052 (1991-05-01)
1. The aim of this investigation was to study the relationship between contractile responsiveness, activation of the L-arginine pathway and tissue levels of guanosine 3':5'cyclic monophosphate (cylic GMP) in aortic rings removed from rats 4 h after intraperitoneal administration of
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持