A6751
N -乙酰基- L -酪氨酸乙酯 一水合物
≥98%, suitable for ligand binding assays
别名:
ATEE
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关于此项目
经验公式（希尔记法）:
C13H17NO4 · H2O
化学文摘社编号:
分子量:
269.29
Beilstein:
2217900
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26
产品名称
N -乙酰基- L -酪氨酸乙酯 一水合物,
方案
≥98%
质量水平
表单
powder
技术
ligand binding assay: suitable
颜色
white
储存温度
−20°C
SMILES字符串
CCOC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O
InChI
1S/C13H17NO4/c1-3-18-13(17)12(14-9(2)15)8-10-4-6-11(16)7-5-10/h4-7,12,16H,3,8H2,1-2H3,(H,14,15)/t12-/m0/s1
InChI key
SKAWDTAMLOJQNK-LBPRGKRZSA-N
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一般描述
胰凝乳蛋白酶的底物
应用
N-乙酰-L-酪氨酸乙酯一水合物已用于：
- 作为底物与1M 1-丙醇用于蛋白包覆微晶法(PCMC)固定化Carlsberg蛋白酶催化的酯交换反应
- 检测蛋白包覆微晶法(PCMC)固定化枯草杆菌蛋白酶Carlsberg的性能
- 作为底物用于枯草杆菌蛋白酶的交联酶晶体(CLEC)的活性筛选
生化/生理作用
N-乙酰基-L-酪氨酸乙酯是 N-末端和 C-末端保护的 L-酪氨酸，其可用于交联研究以及作为检测、分化和/或表征各种蛋白酶和酯酶的底物。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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To evaluate if unconjugated bilirubin (UB) inhibits C1 esterase activity. Esterase activity was evaluated by C1-mediated hydrolysis of N-acetyl-L-tyrosine ethyl ester, and binding of UB to C1r and C1s was assessed by dot-blot analysis. UB inhibited C1 enzymatic activity. C1r
Stability of protein-coated microcrystals in organic solvents
Kreiner M, et al.
Journal of Molecular Catalysis. B, Enzymatic, 33(3-6) (33)
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Biotechnology and bioengineering, 87(1), 24-33 (2004-06-24)
Recently, we reported a new high-activity biocatalyst for use in organic media termed protein-coated microcrystals (PCMC) (Kreiner et al. [2001] Chem Commun 12:1096-1097). These novel particles consist of water-soluble micron-sized crystalline particles coated with the given biocatalyst(s) and are prepared
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