Merck
CN

A6779

Sigma-Aldrich

高碘酸氧化腺苷 5′-三磷酸 钠盐

≥97%

登录to View Organizational & Contract Pricing

Select a Size

Change View
别名:
oATP, 腺苷 5′-三磷酸-2′,3′-二醛
Empirical Formula (Hill Notation):
C10H14N5O13P3
CAS号:
分子量:
505.17
MDL编号:
eCl@ss:
32160414
PubChem化学物质编号:
NACRES:
NA.51

生物来源

bacterial (corynebacterium sp)

质量水平

检测方案

≥97%

形式

powder

储存温度

−20°C

SMILES string

[Na].Nc1ncnc2n(cnc12)[C@H](O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=O)C=O

InChI

1S/C10H14N5O13P3.Na.H/c11-9-8-10(13-4-12-9)15(5-14-8)7(2-17)26-6(1-16)3-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h1-2,4-7H,3H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/t6-,7+;;/m0../s1

InChI key

IHQATUPGVKMGLT-AUCRBCQYSA-N

比较类似商品

查看完整比较结果

显示差异

1 of 4

此商品
A6904A5638A9376
assay

≥97%

assay

90-95%

assay

≥95%

assay

≥93%

form

powder

form

solid

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

一般描述

腺苷-5′-三磷酸-2′,3′-二醛是二醛的一种衍生物。

应用

腺苷-5′-三磷酸,高碘酸氧化钠盐已被用于:
  • 作为嘌呤能受体的拮抗剂(P2×7抑制P2×7通路)
  • 作为通过Ca2+评估P2x7-R活性的非特异性激动剂
  • 评估细胞内ATP水平升高的生理意义
  • 评估Flcn缺陷细胞中用于破骨细胞生成的P2rx7表达升高的生理意义

生化/生理作用

腺苷-5′-三磷酸-2′,3′-二醛被认为是P2×7受体的一种抑制剂。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

在网站页面上,产品编号会附带包装尺寸/数量一起显示(例如:T1503-25G)。请确保 在“产品编号”字段中仅输入产品编号 (示例: T1503).

示例

T1503
货号
-
25G
包装规格/数量

其它示例:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

遇到问题?欢迎随时联系我们技术服务 寻求帮助

批号可以在产品标签上"批“ (Lot或Batch)字后面找到。

Aldrich 产品

  • 如果您查询到的批号为 TO09019TO 等,请输入去除前两位字母的批号:09019TO。

  • 如果您查询到的批号含有填充代码(例如05427ES-021),请输入去除填充代码-021的批号:05427ES。

  • 如果您查询到的批号含有填充代码(例如 STBB0728K9),请输入去除填充代码K9的批号:STBB0728。

未找到您寻找的产品?

部分情况下,可能未在线提供COA。如果搜索不到COA,可在线索取。

索取COA

Ursula Schenk et al.
Science signaling, 1(39), ra6-ra6 (2008-10-02)
T cell receptor (TCR) stimulation results in the influx of Ca(2+), which is buffered by mitochondria and promotes adenosine triphosphate (ATP) synthesis. We found that ATP released from activated T cells through pannexin-1 hemichannels activated purinergic P2X receptors (P2XRs) to
Searching Novel Therapeutic Targets for Scleroderma: P2X7-Receptor Is Up-regulated and Promotes a Fibrogenic Phenotype in Systemic Sclerosis Fibroblasts.
Daniela Gentile et al.
Frontiers in pharmacology, 8, 638-638 (2017-09-29)
William Foulsham et al.
Scientific reports, 9(1), 8617-8617 (2019-06-15)
Adenosine triphosphate (ATP) is released into the extracellular environment during transplantation, and acts via purinergic receptors to amplify the alloimmune response. Here, using a well-established murine model of allogeneic corneal transplantation, we investigated the immunomodulatory mechanisms of the purinergic receptor
Effect of nucleotide analogues on rotavirus transcription and replication
Pizarro JM, et al.
Virology, 184(2), 768-772 (1991)
Xuejing Cui et al.
Small (Weinheim an der Bergstrasse, Germany), 12(43), 5998-6011 (2016-09-21)
Exocytosis of single-walled carbon nanotubes (SWCNTs) determines therapeutic efficiency and toxicity of nanoproducts but its underlying mechanism remains elusive. In this study, it is found that the exocytosis mechanism of SWCNTs is mediated mainly through the activation of P2X7 receptor

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门