A6779
高碘酸氧化腺苷 5′-三磷酸 钠盐
≥97%, bacterial (corynebacterium sp), powder
别名:
oATP, 腺苷 5′-三磷酸-2′,3′-二醛
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关于此项目
经验公式（希尔记法）:
C10H14N5O13P3
化学文摘社编号:
分子量:
505.17
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.51
MDL number:
Assay:
≥97%
Biological source:
bacterial (corynebacterium sp)
Form:
powder
Storage temp.:
−20°C
产品名称
高碘酸氧化腺苷 5′-三磷酸 钠盐, ≥97%
SMILES string
[Na].Nc1ncnc2n(cnc12)[C@H](O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=O)C=O
InChI key
IHQATUPGVKMGLT-AUCRBCQYSA-N
InChI
1S/C10H14N5O13P3.Na.H/c11-9-8-10(13-4-12-9)15(5-14-8)7(2-17)26-6(1-16)3-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h1-2,4-7H,3H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/t6-,7+;;/m0../s1
biological source
bacterial (corynebacterium sp)
assay
≥97%
form
powder
storage temp.
−20°C
Quality Level
相关类别
Application
腺苷-5′-三磷酸，高碘酸氧化钠盐已被用于：
- 作为嘌呤能受体的拮抗剂（P2×7抑制P2×7通路）
- 作为通过Ca2+评估P2x7-R活性的非特异性激动剂
- 评估细胞内ATP水平升高的生理意义
- 评估Flcn缺陷细胞中用于破骨细胞生成的P2rx7表达升高的生理意义
Biochem/physiol Actions
腺苷-5′-三磷酸-2′，3′-二醛被认为是P2×7受体的一种抑制剂。
General description
腺苷-5′-三磷酸-2′，3′-二醛是二醛的一种衍生物。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Xuejing Cui et al.
Small (Weinheim an der Bergstrasse, Germany), 12(43), 5998-6011 (2016-09-21)
Exocytosis of single-walled carbon nanotubes (SWCNTs) determines therapeutic efficiency and toxicity of nanoproducts but its underlying mechanism remains elusive. In this study, it is found that the exocytosis mechanism of SWCNTs is mediated mainly through the activation of P2X7 receptor
Effect of nucleotide analogues on rotavirus transcription and replication
Pizarro JM, et al.
Virology, 184(2), 768-772 (1991)
Liver X receptor beta activation induces pyroptosis of human and murine colon cancer cells
Derangere V, et al.
Cell Death and Differentiation, 21(12), 1914-1914 (2014)
Folliculin Regulates Osteoclastogenesis Through Metabolic Regulation
Baba M, et al.
Journal of Bone and Mineral Research, 33(10), 1785-1798 (2018)
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