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A6926

3-氨基-9-乙基咔唑

Name: 3-氨基-9-乙基咔唑
Brand: SIGMA

chromogenic, tablet

别名:

9-乙基咔唑-3-胺, AEC

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关于此项目

经验公式（希尔记法）:

C₁₄H₁₄N₂

化学文摘社编号:

132-32-1

分子量:

210.27

NACRES:

NA.83

PubChem Substance ID:

24891156

UNSPSC Code:

12352204

EC Number:

205-057-7

MDL number:

MFCD00004964

Beilstein/REAXYS Number:

174969

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产品名称

3-氨基-9-乙基咔唑, tablet

form

tablet

Quality Level

200

solubility

DMF: 1 tablet/5 mL

SMILES string

CCn1c2ccccc2c3cc(N)ccc13

InChI

1S/C14H14N2/c1-2-16-13-6-4-3-5-11(13)12-9-10(15)7-8-14(12)16/h3-9H,2,15H2,1H3

InChI key

OXEUETBFKVCRNP-UHFFFAOYSA-N

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General description

3-氨基-9-乙基咔唑是一种色原体。

Application

在免疫组织化学中，3-氨基-9-乙基咔唑（AEC）已被用作使细胞成像的显色剂。它也可用作酶联免疫吸附斑点（ELISpot）的底物。

Biochem/physiol Actions

3-氨基-9-乙基咔唑是一种过氧化物酶底物，适用于免疫印迹法和免疫组织化学中的染色步骤。该底物能生成不溶性红色终产物，可直观地观察到。

Preparation Note

每片含有20 mg底物。

pictograms

GHS06,GHS08

signalword

Danger

hcodes

H301,H350

pcodes

P202 - P264 - P280 - P301 + P310 - P405 - P501

Hazard Classifications

Acute Tox. 3 Oral - Carc. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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McLaughlin LP, et al.

Cytotherapy, 18(12), 1515-1524 (2016)

Host tissue and glycan binding specificities of avian viral attachment proteins using novel avian tissue microarrays.

Iresha N Ambepitiya Wickramasinghe et al.

PloS one, 10(6), e0128893-e0128893 (2015-06-04)

The initial interaction between viral attachment proteins and the host cell is a critical determinant for the susceptibility of a host for a particular virus. To increase our understanding of avian pathogens and the susceptibility of poultry species, we developed

Using multiple online databases to help identify microRNAs regulating the airway epithelial cell response to a virus-like stimulus.

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Respirology (Carlton, Vic.), 20(8), 1206-1212 (2015-08-21)

Exacerbations of allergic asthma are often triggered by respiratory viral infections. We have previously shown that in a T-helper type 2 (Th2)-biased cytokine environment, mouse and human airway epithelial cells (AEC) exhibit increased expression of pro-inflammatory and anti-viral genes in

Active immunosurveillance in the tumor microenvironment of colorectal cancer is associated with low frequency tumor budding and improved outcome.

Viktor H Koelzer et al.

Translational research : the journal of laboratory and clinical medicine, 166(2), 207-217 (2015-03-24)

Tumor budding (single tumor cells or small tumor cell clusters) at the invasion front of colorectal cancer (CRC) is an adverse prognostic indicator linked to epithelial-mesenchymal transition. This study characterized the immunogenicity of tumor buds by analyzing the expression of

Autotaxin Derived From Lipoprotein(a) and Valve Interstitial Cells Promotes Inflammation and Mineralization of the Aortic Valve.

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Mendelian randomization studies have highlighted that lipoprotein(a) [Lp(a)] was associated with calcific aortic valve disease (CAVD). Lp(a) transports oxidized phospholipids with a high content in lysophosphatidylcholine. Autotaxin (ATX) transforms lysophosphatidylcholine into lysophosphatidic acid. We hypothesized that ATX-lysophosphatidic acid could promote

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NBT-BCIP substrate system aids in western blotting and immunohistological staining, producing a blue-purple insoluble end product.

比色碱性磷酸酶和过氧化物酶底物检测系统

硝基蓝四唑（NBT）可与碱性磷酸酶底物5-溴-4-氯-3-吲哚基磷酸盐（BCIP）一起用于蛋白印迹和免疫组织染色程序。这些底物系统产生不溶的NBT二甲终产物，其颜色为蓝至紫色，可以通过视觉观察到。

全球贸易项目编号

货号	GTIN
A6926-50TAB	04061835553549
A6926-100TAB	04061833383049
A6926-5TAB	04061833383056

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